DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ttm50 and Ctdsp2

DIOPT Version :9

Sequence 1:	NP_001303557.1	Gene:	ttm50 / 31266	FlyBaseID:	FBgn0250874	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_001106941.1	Gene:	Ctdsp2 / 52468	MGIID:	1098748	Length:	270	Species:	Mus musculus

Alignment Length:	211	Identity:	64/211 - (30%)
Similarity:	93/211 - (44%)	Gaps:	25/211 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 EFTHKPLVQQYLQRMWKSIHYYQRMIQEPSRAKLLPDPLKPPYVQPRYTLVLEMKDVLVHPDW-- 244
            |.|||.......:........|| ..|.|... |||:..:..  |.|..:|:::.:.|||..:
Mouse    58 ELTHKEEANTIAKSDLLQCLQYQ-FYQIPGTC-LLPEVTEQD--QGRICVVIDLDETLVHSSFKP 118

  Fly   245 ---------------TYQTGWRFKKRPGVDHFLAECAKDFEIVVFTAEQGMTVFPILDALDPNGY 294
                           |:|.  ...|||.||.||....:.||.|:|||.......|:.|.||..|.
Mouse   119 INNADFIVPVEIEGTTHQV--YVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCGV 181

  Fly   295 IMYRLVRDATHFVDGHHVKNLDNLNRDLKKVIVVDWDANATKMHPDNTFGLARWHGNDDDGQLLD 359
            ...||.|:|..|..|.:||:|..|.|||:|.:::|....:...||:|...:..|..:..|.:||:
Mouse   182 FRARLFREACVFHQGCYVKDLSRLGRDLRKTVILDNSPASYIFHPENAVPVQSWFDDMADTELLN 246

  Fly   360 LIAFLKIIAQNNVDDV 375
            ||...:.:  :..|||
Mouse   247 LIPVFEEL--SGTDDV 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ttm50	NP_001303557.1	CPDc	227..355	CDD:214729	44/144 (31%)
Ctdsp2	NP_001106941.1	HIF-SF_euk	100..259	CDD:274055	49/162 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810