DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dwg and TFIIIA

DIOPT Version :9

Sequence 1:	NP_477338.3	Gene:	dwg / 31265	FlyBaseID:	FBgn0000520	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_001322779.1	Gene:	TFIIIA / 843536	AraportID:	AT1G72050	Length:	427	Species:	Arabidopsis thaliana

Alignment Length:	381	Identity:	87/381 - (22%)
Similarity:	142/381 - (37%)	Gaps:	108/381 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   272 EHLLPEAEDVCEDEDFLEES-LDSAPPTAGEALPYVCTVCQKAFRQQCRLNQHMRSHVDEKQYEC 335
            |.:.| :..|....|..||: :|.......:...|:|..|..:..:...:.:|::||   .|.|.
plant     2 EEINP-SSSVDNKRDMAEEAKVDVKTSAKKDIRNYLCQYCGISRSKNYLITKHIQSH---HQMEL 62

  Fly   336 EECGKRLKHLRNYKEHMLTHTNVKPHQCSICGRFYRTTSSLAVHKRTHAEKKPYNC--DQCGRGY 398
            ||       .|:.:...:...:...|.|..||..::..:.|..|.::|:.::.:.|  |.|...|
plant    63 EE-------ERDDEACEVDEESSSNHTCQECGAEFKKPAHLKQHMQSHSLERSFTCYVDDCAASY 120

  Fly   399 AAFDHLRRHKLTHTGERPYAC--DLCDKAYYDSSSLRQH-KISHT-------------GKKAFTC 447
            ...|||.||.|||.| :.:.|  :.|...:....::.:| |..|:             |.|..||
plant   121 RRKDHLNRHLLTHKG-KLFKCPKENCKSEFSVQGNVGRHVKKYHSNDNRDKDNTGLGDGDKDNTC 184

  Fly   448 ------EICGVGLSQK--------------SGYKKHMMVHSGVKAHKCDV--CGHAFTFTSNL-- 488
                  |..|.|..:|              :|..:.....:|.|...|..  ||.||.:.|.|
plant   185 KGDDDKEKSGSGGCEKENEGNGGSGKDNNGNGDSQPAECSTGQKQVVCKEIGCGKAFKYPSQLQK 249

  Fly   489 --NAHVRLHSGE---------KPFKCEVCVKAF----------------PTKKRLASHMRVHNKE 526
              ::||:|.|.|         |.|..|.|:|:.                ..||.:..|:|.|:::
plant   250 HQDSHVKLDSVEAFCSEPGCMKYFTNEECLKSHIRSCHQHINCEICGSKHLKKNIKRHLRTHDED 314

  Fly   527 SPVTATVAVQSINPPSRQAGAEGATGGGATGGSPTGGGATGGSATNL--HITEVHE 580
            |           :|...:...||.:             :|...|:||  |:..||:
plant   315 S-----------SPGEIKCEVEGCS-------------STFSKASNLQKHMKAVHD 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dwg	NP_477338.3	zf-AD	14..91	CDD:214871
		COG5048	<297..451	CDD:227381	41/177 (23%)
		C2H2 Zn finger	307..327	CDD:275368	3/19 (16%)
		C2H2 Zn finger	335..355	CDD:275368	3/19 (16%)
		C2H2 Zn finger	363..383	CDD:275368	5/19 (26%)
		COG5048	<387..523	CDD:227381	50/204 (25%)
		C2H2 Zn finger	391..411	CDD:275368	10/21 (48%)
		zf-H2C2_2	403..426	CDD:290200	10/24 (42%)
		C2H2 Zn finger	419..439	CDD:275368	4/22 (18%)
		C2H2 Zn finger	447..467	CDD:275368	6/39 (15%)
		C2H2 Zn finger	475..495	CDD:275368	9/25 (36%)
		zf-H2C2_2	487..510	CDD:290200	11/35 (31%)
		C2H2 Zn finger	503..523	CDD:275368	7/35 (20%)
TFIIIA	NP_001322779.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I2264
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050