DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dwg and DOT5

DIOPT Version :9

Sequence 1:	NP_477338.3	Gene:	dwg / 31265	FlyBaseID:	FBgn0000520	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_172787.1	Gene:	DOT5 / 837889	AraportID:	AT1G13290	Length:	302	Species:	Arabidopsis thaliana

Alignment Length:	302	Identity:	63/302 - (20%)
Similarity:	103/302 - (34%)	Gaps:	76/302 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 HQLAQSGDQQEEHITMESVHEFQPAEVEYVTIKNEFETIVTEEDEFE--VMNDSGAHDAILDCQM 245
            :|.:.|||:....:::      .|...:|.:......|..:.:.||.  :.|.:|...|:    .
plant     5 NQYSFSGDEDSVVLSL------GPPGQQYPSHNKPTSTKPSSDHEFNHPLTNPNGVTVAL----H 59

  Fly   246 IVIPAEGAIDEVIGEETLELEGDGRE-------EHLLPEAEDVCEDEDFLEESLDSAPPTAGEAL 303
            |..|:.       .:|||. .|:.:|       ::.:|....:.            ..||
plant    60 IGPPSS-------DKETLS-GGNNQEGLTARQGQYWIPSLSQIL------------VGPT----- 99

  Fly   304 PYVCTVCQKAFRQQCRLNQHMRSHVDEKQYECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGR 368
            .:.|:||.|.|.:...:..||..|  ..||.     |..:.||..|    :.:::....|..|..
plant   100 QFSCSVCNKTFNRFNNMQMHMWGH--GSQYR-----KGPESLRGTK----SSSSILRLPCYCCAE 153

  Fly   369 FYRTTSSLAVHKRTHAEKKPYNCDQCGRGYAAFDHLRRHKLTHTGERPYAC-DLCDKAYYDSSSL 432
            ..:....       |...||..         .|..|:.|.....|.:|:.| ..|:|.:......
plant   154 GCKNNID-------HPRSKPLK---------DFRTLQTHYKRKHGAKPFRCRKKCEKTFAVRGDW 202

  Fly   433 RQHKISHTGKKAFTCEICGVGLSQKSGYKKHMMVH-SGVKAH 473
            |.|: .:.||..| | :||.....|...|.|:... .|..||
plant   203 RTHE-KNCGKLWF-C-VCGSDFKHKRSLKDHVRAFGDGHAAH 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dwg	NP_477338.3	zf-AD	14..91	CDD:214871
		COG5048	<297..451	CDD:227381	35/154 (23%)
		C2H2 Zn finger	307..327	CDD:275368	7/19 (37%)
		C2H2 Zn finger	335..355	CDD:275368	4/19 (21%)
		C2H2 Zn finger	363..383	CDD:275368	2/19 (11%)
		COG5048	<387..523	CDD:227381	24/89 (27%)
		C2H2 Zn finger	391..411	CDD:275368	3/19 (16%)
		zf-H2C2_2	403..426	CDD:290200	7/23 (30%)
		C2H2 Zn finger	419..439	CDD:275368	5/20 (25%)
		C2H2 Zn finger	447..467	CDD:275368	6/19 (32%)
		C2H2 Zn finger	475..495	CDD:275368
		zf-H2C2_2	487..510	CDD:290200
		C2H2 Zn finger	503..523	CDD:275368
DOT5	NP_172787.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910