DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dwg and AT5G22890

DIOPT Version :9

Sequence 1:	NP_477338.3	Gene:	dwg / 31265	FlyBaseID:	FBgn0000520	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_197680.2	Gene:	AT5G22890 / 832353	AraportID:	AT5G22890	Length:	373	Species:	Arabidopsis thaliana

Alignment Length:	437	Identity:	84/437 - (19%)
Similarity:	143/437 - (32%)	Gaps:	140/437 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 IEMLNEEQE-------NVANLDEELAEEDRRIFAMTVDEEEEFLTEEVDQDD----------ELS 179
            |.|:|.::.       ::::...|.:...::|:...|....   |:.::.||          .|.
plant     3 IHMMNRDEHIAKKVEGSISSFSGETSTSSKQIYVNPVTTTG---TKSMEDDDVSLSLLYNLSTLH 64

  Fly   180 EEEHQL-------------------------AQSGDQQEEHITMES--VHEFQPAEVEYVTIKNE 217
            |:.||:                         |..|...:|.||..|  ::..|..::......|:
plant    65 EKVHQIQSLVSFYMVSTNNINQSSGSTSLAVANIGSLVQEIITAASSMLYTCQQLQIGSNNNNND 129

  Fly   218 FETIVTEED---EFEVMNDSGAHDAILD-CQMIVIPAEGAI---DEVIGEETLELEGDGREEHLL 275
            .:...|.:.   ||........||.:.: ..:..:...|.|   |:.:.....|.....:::|
plant   130 IDNDQTVDAMVLEFSRQETDPGHDFVQESTNLFGVQERGQISFPDQNLDWYNTETINPKKDKH-- 192

  Fly   276 PEAEDVCEDEDFLEESLDSAPPTAGEALPYVCTVCQKAFRQQCRLNQHMRSHVDEKQYECEEC-- 338
             .::......|.||  ||.|...|  ...:.|.:|.|.|::...|..|||:|.||  |:..|.
plant   193 -RSKPSSGSYDILE--LDVADLLA--KYTHYCQICGKGFKRDANLRMHMRAHGDE--YKTREALI 250

  Fly   339 ---------GKRL-KHLRNYKEH----MLTHTNVKPHQCSICGRFYRTTSSLAVHKRTHAEKKPY 389
                     |..| ||..:..:|    ...|...:|.:..||.:.:        :||:|..|. |
plant   251 SPTSQDKKGGYSLKKHYYSCPQHGCRWNQRHEKFQPLKSVICAKNH--------YKRSHCPKM-Y 306

  Fly   390 NCDQCG-RGYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLRQHKISHTGKKAFTCEICGVG 453
            .|.:|. :.::....||.|: .|.|:..:.|.                             ||..
plant   307 MCRRCSVKHFSVLSDLRTHE-KHCGDIKWVCS-----------------------------CGTK 341

  Fly   454 LSQKSGYKKHMMVHSGVKAHKCDVCGHAFTFTSNLNAHVRLHSGEKP 500
            .|:|.....|:.:..|                     ||..|...||
plant   342 FSRKDKLMSHVSLFLG---------------------HVPAHGSSKP 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dwg	NP_477338.3	zf-AD	14..91	CDD:214871
		COG5048	<297..451	CDD:227381	36/170 (21%)
		C2H2 Zn finger	307..327	CDD:275368	8/19 (42%)
		C2H2 Zn finger	335..355	CDD:275368	6/35 (17%)
		C2H2 Zn finger	363..383	CDD:275368	4/19 (21%)
		COG5048	<387..523	CDD:227381	20/115 (17%)
		C2H2 Zn finger	391..411	CDD:275368	5/20 (25%)
		zf-H2C2_2	403..426	CDD:290200	6/22 (27%)
		C2H2 Zn finger	419..439	CDD:275368	1/19 (5%)
		C2H2 Zn finger	447..467	CDD:275368	5/19 (26%)
		C2H2 Zn finger	475..495	CDD:275368	2/19 (11%)
		zf-H2C2_2	487..510	CDD:290200	5/14 (36%)
		C2H2 Zn finger	503..523	CDD:275368
AT5G22890	NP_197680.2	zf-C2H2	217..239	CDD:333835	8/21 (38%)
		C2H2 Zn finger	219..239	CDD:275368	8/19 (42%)
		C2H2 Zn finger	308..328	CDD:275368	5/20 (25%)
		C2H2 Zn finger	336..352	CDD:275368	5/44 (11%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910