DRSC/TRiP Functional Genomics Resources

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Protein Alignment dwg and ZNF430

DIOPT Version :9

Sequence 1:NP_477338.3 Gene:dwg / 31265 FlyBaseID:FBgn0000520 Length:592 Species:Drosophila melanogaster
Sequence 2:NP_079465.3 Gene:ZNF430 / 80264 HGNCID:20808 Length:570 Species:Homo sapiens


Alignment Length:225 Identity:101/225 - (44%)
Similarity:132/225 - (58%) Gaps:0/225 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly   304 PYVCTVCQKAFRQQCRLNQHMRSHVDEKQYECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGR 368
            ||.|..|.|||:|...|..|...|..||.|.||||||......:...|...||..||::|..|||
Human   260 PYKCEQCGKAFKQSSTLTTHKIIHTGEKPYRCEECGKTFNRSSHLTTHKRIHTGEKPYRCEECGR 324

  Fly   369 FYRTTSSLAVHKRTHAEKKPYNCDQCGRGYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLR 433
            .:..:|.|..||..|..:|||.|::||:.:.....|..||:.|.||:||.|:.|.||:|..|.|.
Human   325 AFNRSSHLTTHKIIHTGEKPYKCEECGKAFNQSSTLTTHKIIHAGEKPYKCEECGKAFYRFSYLT 389

  Fly   434 QHKISHTGKKAFTCEICGVGLSQKSGYKKHMMVHSGVKAHKCDVCGHAFTFTSNLNAHVRLHSGE 498
            :|||.|||:|.:.||.||.|.:..|...||..:|:|.|.:||:.||.||..:|||.||..:|:||
Human   390 KHKIIHTGEKFYKCEECGKGFNWSSTLTKHKRIHTGEKPYKCEQCGKAFNESSNLTAHKIIHTGE 454

  Fly   499 KPFKCEVCVKAFPTKKRLASHMRVHNKESP 528
            ||:|||.|.|||....:|.:|..:|:.|.|
Human   455 KPYKCEECGKAFNRSPKLTAHKVIHSGEKP 484

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dwgNP_477338.3 zf-AD 14..91 CDD:214871
COG5048 <297..451 CDD:227381 64/146 (44%)
C2H2 Zn finger 307..327 CDD:275368 8/19 (42%)
C2H2 Zn finger 335..355 CDD:275368 7/19 (37%)
C2H2 Zn finger 363..383 CDD:275368 8/19 (42%)
COG5048 <387..523 CDD:227381 64/135 (47%)
C2H2 Zn finger 391..411 CDD:275368 6/19 (32%)
zf-H2C2_2 403..426 CDD:290200 11/22 (50%)
C2H2 Zn finger 419..439 CDD:275368 10/19 (53%)
C2H2 Zn finger 447..467 CDD:275368 8/19 (42%)
C2H2 Zn finger 475..495 CDD:275368 10/19 (53%)
zf-H2C2_2 487..510 CDD:290200 14/22 (64%)
C2H2 Zn finger 503..523 CDD:275368 8/19 (42%)
ZNF430NP_079465.3 KRAB 35..96 CDD:214630
KRAB 35..74 CDD:279668
COG5048 202..562 CDD:227381 101/225 (45%)
C2H2 Zn finger 207..227 CDD:275368
C2H2 Zn finger 235..255 CDD:275368
zf-H2C2_2 248..272 CDD:290200 7/11 (64%)
C2H2 Zn finger 263..283 CDD:275368 8/19 (42%)
zf-H2C2_2 276..300 CDD:290200 12/23 (52%)
C2H2 Zn finger 291..311 CDD:275368 7/19 (37%)
zf-H2C2_2 303..328 CDD:290200 9/24 (38%)
C2H2 Zn finger 319..339 CDD:275368 8/19 (42%)
zf-H2C2_2 331..356 CDD:290200 10/24 (42%)
C2H2 Zn finger 347..367 CDD:275368 6/19 (32%)
C2H2 Zn finger 375..395 CDD:275368 10/19 (53%)
C2H2 Zn finger 403..423 CDD:275368 8/19 (42%)
zf-H2C2_2 416..439 CDD:290200 10/22 (45%)
C2H2 Zn finger 431..451 CDD:275368 10/19 (53%)
zf-H2C2_2 443..468 CDD:290200 16/24 (67%)
C2H2 Zn finger 459..479 CDD:275368 8/19 (42%)
zf-H2C2_2 472..496 CDD:290200 5/13 (38%)
C2H2 Zn finger 487..507 CDD:275368
C2H2 Zn finger 515..535 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24384
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.010

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