DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dwg and LOC797855

DIOPT Version :9

Sequence 1:	NP_477338.3	Gene:	dwg / 31265	FlyBaseID:	FBgn0000520	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_001373180.1	Gene:	LOC797855 / 797855	-ID:	-	Length:	282	Species:	Danio rerio

Alignment Length:	321	Identity:	91/321 - (28%)
Similarity:	146/321 - (45%)	Gaps:	59/321 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 IKNEFETIVTEEDEF-----EVMNDSGAHDAILDCQMIVIPAEGAIDEVIGEETLELE-GDGREE 272
            ||.||   :.:|:|:     ...|::|..|                     |:|.:.| |..|:|
Zfish     2 IKMEF---IKKENEYLRDPEPSRNNNGETD---------------------EQTDQNEYGVERQE 42

  Fly   273 HLLPEAEDV-CEDEDFLEESLDS----APPTAGEALPYVCTVCQKAFRQQCRLNQHMRSHVDEK- 331
               |..:|. |   ||..:..::    .|...|..:            ..|  .||.:..:.|.
Zfish    43 ---PNEQDKHC---DFKTKRRNARKLQTPQRCGTLI------------DDC--EQHQQETLTETG 87

  Fly   332 QYECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGRFYRTTSSLAVHKRTHAEKKPYNCDQCGR 396
            .:.|.||||......:.|.|...||. ||::||.|.:.:..::::..|:|.|..:  :.|.:||.
Zfish    88 HHVCLECGKSFSRAYSLKLHQRGHTE-KPYKCSYCEKSFSLSATMRKHERVHTGE--FICAECGH 149

  Fly   397 GYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLRQHKISHTGKKAFTCEICGVGLSQKSGYK 461
            .:::...|:||.:.||.||||||.||:|.:......:||:.:|..::...|..||...::....|
Zfish   150 DFSSSPSLKRHMIMHTNERPYACLLCEKRFTRLDQFKQHQKTHADERDHVCLQCGKSFNRSDHLK 214

  Fly   462 KHMMVHSGVKAHKCDVCGHAFTFTSNLNAHVRLHSGEKPFKCEVCVKAFPTKKRLASHMRV 522
            .|.:.|:|||.|||..|...||..|::..|..:|:||:|:.|..|.|:|.....|..||::
Zfish   215 SHQITHTGVKPHKCSYCEKTFTQASSMKKHQSIHTGERPYCCPACQKSFRRSDSLIKHMKI 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dwg	NP_477338.3	zf-AD	14..91	CDD:214871
		COG5048	<297..451	CDD:227381	43/154 (28%)
		C2H2 Zn finger	307..327	CDD:275368	3/19 (16%)
		C2H2 Zn finger	335..355	CDD:275368	7/19 (37%)
		C2H2 Zn finger	363..383	CDD:275368	5/19 (26%)
		COG5048	<387..523	CDD:227381	48/136 (35%)
		C2H2 Zn finger	391..411	CDD:275368	6/19 (32%)
		zf-H2C2_2	403..426	CDD:290200	14/22 (64%)
		C2H2 Zn finger	419..439	CDD:275368	6/19 (32%)
		C2H2 Zn finger	447..467	CDD:275368	5/19 (26%)
		C2H2 Zn finger	475..495	CDD:275368	6/19 (32%)
		zf-H2C2_2	487..510	CDD:290200	8/22 (36%)
		C2H2 Zn finger	503..523	CDD:275368	7/20 (35%)
LOC797855	NP_001373180.1	C2H2 Zn finger	91..111	CDD:275368	7/19 (37%)
		COG5048	<114..272	CDD:227381	54/159 (34%)
		C2H2 Zn finger	118..138	CDD:275368	5/19 (26%)
		C2H2 Zn finger	144..164	CDD:275368	6/19 (32%)
		C2H2 Zn finger	172..192	CDD:275368	6/19 (32%)
		C2H2 Zn finger	200..220	CDD:275368	5/19 (26%)
		C2H2 Zn finger	228..248	CDD:275368	6/19 (32%)
		C2H2 Zn finger	256..275	CDD:275368	7/18 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910