DRSC/TRiP Functional Genomics Resources

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Protein Alignment dwg and ZNF655

DIOPT Version :9

Sequence 1:NP_477338.3 Gene:dwg / 31265 FlyBaseID:FBgn0000520 Length:592 Species:Drosophila melanogaster
Sequence 2:NP_001077425.1 Gene:ZNF655 / 79027 HGNCID:30899 Length:526 Species:Homo sapiens


Alignment Length:523 Identity:123/523 - (23%)
Similarity:198/523 - (37%) Gaps:132/523 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   123 FDSTEEYVMIEMLNEEQENVANLDEELA----------------EEDRRIFAMTVDEEEEFLTEE 171
            |.|.|  ...|.|:.|.:.|.:.|.|..                |:|.::|.:      |..|.|
Human    17 FQSLE--TQSECLSPEPQFVQDTDMEQGLTGGFPISKPDGISQLEQDLQVFDL------ETKTRE 73

  Fly   172 VDQDD-----------------ELSEE-----------EHQLAQSGDQQEEHITMESVHEFQPAE 208
            |.:||                 ::|||           :|.:.|..:.:|.:.:.:.:...|...
Human    74 VLRDDCSDGETREENKLLIPKQKISEEVHSYKVRVGRLKHDITQVPETREVYKSEDRLERLQEIL 138

  Fly   209 VEYVTIKNEFETIVTEEDEFEVMNDSGAH--------DAILDCQMIVIPAEGAIDEVIGEETL-E 264
            .:::.::.||..|...::.|....::..|        |:.:|....|:..:...|....:.:. :
Human   139 RKFLYLEREFRQITISKETFTSEKNNECHEPEKSFSLDSTIDADQRVLRIQNTDDNDKYDMSFNQ 203

  Fly   265 LEGDGREEHLLPEAEDVCED---EDFLEESLDSAPPTAGEALP-----YVCTVCQKAFRQQCRLN 321
            ....|:.|||     ::.||   .:..|..:|.:.....|::|     |.|.||.|.|.|...|.
Human   204 NSASGKHEHL-----NLTEDFQSSECKESLMDLSHLNKWESIPNTEKSYKCDVCGKIFHQSSALT 263

  Fly   322 QHMRSHVDEKQYECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGRFYRT-------TSSLAVH 379
            :|.|.|..||.|:|:||.|......:...|...||..||::|....:....       :|.:..|
Human   264 RHQRIHTREKPYKCKECEKSFSQSSSLSRHKRIHTREKPYKCEASDKSCEASDKSCSPSSGIIQH 328

  Fly   380 KRTHAEKKPYNCDQCGRGYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLRQHKISHTGKKA 444
            |:.|...|.|.|..|.|.::...||.:|:..|. |.|..|.:|...:..:|.|.:|:..|..:||
Human   329 KKIHTRAKSYKCSSCERVFSRSVHLTQHQKIHK-EMPCKCTVCGSDFCHTSYLLEHQRVHHEEKA 392

  Fly   445 ----------------------FTCEICGVGLSQKSGYKKHMMVHSGVKAHKCDVCGHAFTFTSN 487
                                  :||..||......|...:|..:|:|.|||:|:.||.||:.||.
Human   393 YEYDEYGLAYIKQQGIHFREKPYTCSECGKDFRLNSHLIQHQRIHTGEKAHECNECGKAFSQTSC 457

  Fly   488 LNAHVRLHSGE----------------------------KPFKCEVCVKAFPTKKRLASHMRVHN 524
            |..|.::|..|                            |.|.|:|..|....:..|..|..:|.
Human   458 LIQHHKMHRKEKSYECNEYEGSFSHSSDLILQQEVLTRQKAFDCDVWEKNSSQRAHLVQHQSIHT 522

  Fly   525 KES 527
            ||:
Human   523 KEN 525

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dwgNP_477338.3 zf-AD 14..91 CDD:214871
COG5048 <297..451 CDD:227381 51/187 (27%)
C2H2 Zn finger 307..327 CDD:275368 9/19 (47%)
C2H2 Zn finger 335..355 CDD:275368 5/19 (26%)
C2H2 Zn finger 363..383 CDD:275368 4/26 (15%)
COG5048 <387..523 CDD:227381 48/185 (26%)
C2H2 Zn finger 391..411 CDD:275368 6/19 (32%)
zf-H2C2_2 403..426 CDD:290200 8/22 (36%)
C2H2 Zn finger 419..439 CDD:275368 5/19 (26%)
C2H2 Zn finger 447..467 CDD:275368 5/19 (26%)
C2H2 Zn finger 475..495 CDD:275368 9/19 (47%)
zf-H2C2_2 487..510 CDD:290200 9/50 (18%)
C2H2 Zn finger 503..523 CDD:275368 5/19 (26%)
ZNF655NP_001077425.1 COG5048 220..>325 CDD:227381 29/104 (28%)
C2H2 Zn finger 222..241 CDD:275368 3/18 (17%)
C2H2 Zn finger 249..269 CDD:275368 9/19 (47%)
C2H2 Zn finger 277..297 CDD:275368 5/19 (26%)
C2H2 Zn finger 305..360 CDD:275368 13/54 (24%)
C2H2 Zn finger 367..387 CDD:275368 5/19 (26%)
C2H2 Zn finger 417..437 CDD:275368 5/19 (26%)
zf-H2C2_2 429..454 CDD:404364 11/24 (46%)
C2H2 Zn finger 445..465 CDD:275368 9/19 (47%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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