DRSC/TRiP Functional Genomics Resources

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Protein Alignment dwg and VEZF1

DIOPT Version :9

Sequence 1:NP_477338.3 Gene:dwg / 31265 FlyBaseID:FBgn0000520 Length:592 Species:Drosophila melanogaster
Sequence 2:XP_005257700.1 Gene:VEZF1 / 7716 HGNCID:12949 Length:527 Species:Homo sapiens


Alignment Length:327 Identity:87/327 - (26%)
Similarity:129/327 - (39%) Gaps:78/327 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   271 EEHLLPEAEDVCEDEDF-------LEESLDSAPPTAGEAL---------PYVCTVCQKAFRQQCR 319
            :..|||......|..|.       :.:....||.|..:|:         .:|||.|.||||.   
Human    24 QNSLLPLLSSAVEPPDQKPLLPIPITQKPQGAPETLKDAIGIKKEKPKTSFVCTYCSKAFRD--- 85

  Fly   320 LNQHMRSHVDEKQYECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGRFYR------------- 371
             :.|:|.|        |.|...:|.:...|:   |.|.|.|...:|.|...|             
Human    86 -SYHLRRH--------ESCHTGIKLVSRPKK---TPTTVVPLISTIAGDSSRTSLVSTIAGILST 138

  Fly   372 -TTSS-----------------LAVHKRTHAEKKPYNCDQCGRGYAAFDHLRRHKLTHTGERPYA 418
             ||||                 .:|.|.:...||.:.|:.||:.:....||.||||:|:.|:|:.
Human   139 VTTSSSGTNPSSSASTTAMPVTQSVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSHSDEKPFE 203

  Fly   419 CDLCDKAYYDSSSLRQHKISHTG--KKAFTCEICGVGLSQK---SGYKKHMMVHSGVKAHKC--- 475
            |.:|::.:.....:..|..||.|  .|.:||.:||.|.|:.   |.:.||  |||..:..||   
Human   204 CPICNQRFKRKDRMTYHVRSHEGGITKPYTCSVCGKGFSRPDHLSCHVKH--VHSTERPFKCQFS 266

  Fly   476 ---DVCGHAFTFTSNLNAHVRLHSGEKPFKCEVCVKAFPTKKRLASHMRVHNKESPVTATVAVQS 537
               ..|..||.....|..|:..|.|:  ..|.:|.|.. :...:.||::.|.:...:......|.
Human   267 SLMQTCTAAFATKDRLRTHMVRHEGK--VSCNICGKLL-SAAYITSHLKTHGQSQSINCNTCKQG 328

  Fly   538 IN 539
            |:
Human   329 IS 330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dwgNP_477338.3 zf-AD 14..91 CDD:214871
COG5048 <297..451 CDD:227381 53/195 (27%)
C2H2 Zn finger 307..327 CDD:275368 9/19 (47%)
C2H2 Zn finger 335..355 CDD:275368 4/19 (21%)
C2H2 Zn finger 363..383 CDD:275368 9/50 (18%)
COG5048 <387..523 CDD:227381 46/146 (32%)
C2H2 Zn finger 391..411 CDD:275368 9/19 (47%)
zf-H2C2_2 403..426 CDD:290200 11/22 (50%)
C2H2 Zn finger 419..439 CDD:275368 3/19 (16%)
C2H2 Zn finger 447..467 CDD:275368 8/22 (36%)
C2H2 Zn finger 475..495 CDD:275368 6/25 (24%)
zf-H2C2_2 487..510 CDD:290200 7/22 (32%)
C2H2 Zn finger 503..523 CDD:275368 5/19 (26%)
VEZF1XP_005257700.1 C2H2 Zn finger 76..96 CDD:275368 11/31 (35%)
C2H2 Zn finger 176..196 CDD:275368 9/19 (47%)
zf-H2C2_2 188..213 CDD:290200 11/24 (46%)
C2H2 Zn finger 204..224 CDD:275368 3/19 (16%)
C2H2 Zn finger 234..252 CDD:275368 6/17 (35%)
C2H2 Zn finger 263..289 CDD:275368 6/25 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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