| Sequence 1: | NP_477338.3 | Gene: | dwg / 31265 | FlyBaseID: | FBgn0000520 | Length: | 592 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_009060.2 | Gene: | ZIC2 / 7546 | HGNCID: | 12873 | Length: | 532 | Species: | Homo sapiens |
| Alignment Length: | 280 | Identity: | 75/280 - (26%) |
|---|---|---|---|
| Similarity: | 125/280 - (44%) | Gaps: | 49/280 - (17%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 315 RQQCRLNQHMRSHVDEKQYE--CEECGKRLKHLRNYKEHMLTHTNVK----PHQCS-IC------ 366
Fly 367 --GRFYRTTSSLAVHKRTHAEKKPYNC--DQCGRGYAAFDHLRRHKLTHTGERPYACDL--CDKA 425
Fly 426 YYDSSSLRQHKISHTGKKAFTCEICGVGLSQKSGYKKHMMVH----SGVKAHKCDVCGHAFTFTS 486
Fly 487 NLNAHVRLHSGEKPFKCEVCVKAFPTKKRLASHMRVHNKESPVTATVAVQSINPPSRQAGA-EGA 550
Fly 551 TGGGATGGSPTGGGATGGSA 570 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| dwg | NP_477338.3 | zf-AD | 14..91 | CDD:214871 | |
| COG5048 | <297..451 | CDD:227381 | 44/154 (29%) | ||
| C2H2 Zn finger | 307..327 | CDD:275368 | 4/11 (36%) | ||
| C2H2 Zn finger | 335..355 | CDD:275368 | 2/19 (11%) | ||
| C2H2 Zn finger | 363..383 | CDD:275368 | 5/28 (18%) | ||
| COG5048 | <387..523 | CDD:227381 | 39/143 (27%) | ||
| C2H2 Zn finger | 391..411 | CDD:275368 | 7/21 (33%) | ||
| zf-H2C2_2 | 403..426 | CDD:290200 | 12/24 (50%) | ||
| C2H2 Zn finger | 419..439 | CDD:275368 | 6/21 (29%) | ||
| C2H2 Zn finger | 447..467 | CDD:275368 | 6/19 (32%) | ||
| C2H2 Zn finger | 475..495 | CDD:275368 | 2/19 (11%) | ||
| zf-H2C2_2 | 487..510 | CDD:290200 | 2/22 (9%) | ||
| C2H2 Zn finger | 503..523 | CDD:275368 | 4/19 (21%) | ||
| ZIC2 | NP_009060.2 | Necessary for interaction with MDFIC and transcriptional activation or repression. /evidence=ECO:0000250 | 100..255 | 4/6 (67%) | |
| zf_ZIC | 250..295 | CDD:408166 | 9/48 (19%) | ||
| C2H2 Zn finger | 307..327 | CDD:275368 | 4/19 (21%) | ||
| SFP1 | <329..413 | CDD:227516 | 29/83 (35%) | ||
| C2H2 Zn finger | 335..357 | CDD:275368 | 7/21 (33%) | ||
| C2H2 Zn finger | 365..387 | CDD:275368 | 6/21 (29%) | ||
| C2H2 Zn finger | 395..415 | CDD:275368 | 6/19 (32%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 406..452 | 12/64 (19%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 475..532 | 15/30 (50%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||