DRSC/TRiP Functional Genomics Resources

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Protein Alignment dwg and ZNF723

DIOPT Version :9

Sequence 1:NP_477338.3 Gene:dwg / 31265 FlyBaseID:FBgn0000520 Length:592 Species:Drosophila melanogaster
Sequence 2:XP_024307421.1 Gene:ZNF723 / 646864 HGNCID:32286 Length:547 Species:Homo sapiens


Alignment Length:224 Identity:100/224 - (44%)
Similarity:127/224 - (56%) Gaps:0/224 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly   305 YVCTVCQKAFRQQCRLNQHMRSHVDEKQYECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGRF 369
            |.|..|.|||....:||.|.|.|..||.|:||||||......:...|...||..||::|..||:.
Human   201 YKCEECGKAFSVPSKLNNHKRIHTGEKPYKCEECGKAFNVSSSLNNHKRIHTGEKPYKCEECGKT 265

  Fly   370 YRTTSSLAVHKRTHAEKKPYNCDQCGRGYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLRQ 434
            :...|||..|||.|..:|||.|.:||:.:..|..|..||..||||:||.|:.|.||:...|.|..
Human   266 FNMFSSLNNHKRIHTGEKPYKCKECGKAFNVFSSLNNHKRIHTGEKPYKCEECGKAFNQPSHLAT 330

  Fly   435 HKISHTGKKAFTCEICGVGLSQKSGYKKHMMVHSGVKAHKCDVCGHAFTFTSNLNAHVRLHSGEK 499
            ||..|||:|.:.||.||...||.|....|..:|:|.|.:||:.||.||..:.:|..|.|:|:|||
Human   331 HKRIHTGEKLYKCEECGKAFSQSSHITTHKRIHTGEKPYKCEECGKAFKVSVHLTTHKRIHTGEK 395

  Fly   500 PFKCEVCVKAFPTKKRLASHMRVHNKESP 528
            |:|||.|.|||.....|.:|..:|..|.|
Human   396 PYKCEECGKAFNQSSALTTHKIIHTGERP 424

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dwgNP_477338.3 zf-AD 14..91 CDD:214871
COG5048 <297..451 CDD:227381 65/145 (45%)
C2H2 Zn finger 307..327 CDD:275368 9/19 (47%)
C2H2 Zn finger 335..355 CDD:275368 7/19 (37%)
C2H2 Zn finger 363..383 CDD:275368 9/19 (47%)
COG5048 <387..523 CDD:227381 62/135 (46%)
C2H2 Zn finger 391..411 CDD:275368 7/19 (37%)
zf-H2C2_2 403..426 CDD:290200 12/22 (55%)
C2H2 Zn finger 419..439 CDD:275368 8/19 (42%)
C2H2 Zn finger 447..467 CDD:275368 8/19 (42%)
C2H2 Zn finger 475..495 CDD:275368 8/19 (42%)
zf-H2C2_2 487..510 CDD:290200 13/22 (59%)
C2H2 Zn finger 503..523 CDD:275368 8/19 (42%)
ZNF723XP_024307421.1 KRAB 4..64 CDD:214630
COG5048 156..504 CDD:227381 100/224 (45%)
C2H2 Zn finger 175..195 CDD:275368
C2H2 Zn finger 203..223 CDD:275368 9/19 (47%)
C2H2 Zn finger 231..251 CDD:275368 7/19 (37%)
C2H2 Zn finger 259..279 CDD:275368 9/19 (47%)
C2H2 Zn finger 287..307 CDD:275368 7/19 (37%)
C2H2 Zn finger 315..335 CDD:275368 8/19 (42%)
C2H2 Zn finger 343..363 CDD:275368 8/19 (42%)
C2H2 Zn finger 371..391 CDD:275368 8/19 (42%)
C2H2 Zn finger 399..419 CDD:275368 8/19 (42%)
C2H2 Zn finger 427..447 CDD:275368
C2H2 Zn finger 455..475 CDD:275368
C2H2 Zn finger 483..503 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24384
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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