DRSC/TRiP Functional Genomics Resources

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Protein Alignment dwg and ZNF415

DIOPT Version :9

Sequence 1:NP_477338.3 Gene:dwg / 31265 FlyBaseID:FBgn0000520 Length:592 Species:Drosophila melanogaster
Sequence 2:XP_024307363.1 Gene:ZNF415 / 55786 HGNCID:20636 Length:678 Species:Homo sapiens


Alignment Length:225 Identity:92/225 - (40%)
Similarity:130/225 - (57%) Gaps:0/225 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly   304 PYVCTVCQKAFRQQCRLNQHMRSHVDEKQYECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGR 368
            ||.|..|.|||..:..|..|...|..:|.|:|.||||......:...|...||..||::|:.||:
Human   450 PYTCKECGKAFSVRSTLTNHQVIHSGKKPYKCNECGKVFSQTSSLATHQRIHTGEKPYKCNECGK 514

  Fly   369 FYRTTSSLAVHKRTHAEKKPYNCDQCGRGYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLR 433
            .:..|||||.|.|.|..:|||.|::||:.::...||..|:..||||:||.|:.|.||:...|:|.
Human   515 VFSQTSSLARHWRIHTGEKPYKCNECGKVFSYNSHLASHRRVHTGEKPYKCNECGKAFSVHSNLT 579

  Fly   434 QHKISHTGKKAFTCEICGVGLSQKSGYKKHMMVHSGVKAHKCDVCGHAFTFTSNLNAHVRLHSGE 498
            .|::.|||:|.:.|..||.|.|..|....|.::|:|.|.:||:.||.:|:...||..|..:|:|:
Human   580 THQVIHTGEKPYKCNQCGKGFSVHSSLTTHQVIHTGEKPYKCNECGKSFSVRPNLTRHQIIHTGK 644

  Fly   499 KPFKCEVCVKAFPTKKRLASHMRVHNKESP 528
            ||:||..|.|:|..:..|..|..:|.||.|
Human   645 KPYKCSDCGKSFSVRPNLFRHQIIHTKEKP 674

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dwgNP_477338.3 zf-AD 14..91 CDD:214871
COG5048 <297..451 CDD:227381 60/146 (41%)
C2H2 Zn finger 307..327 CDD:275368 7/19 (37%)
C2H2 Zn finger 335..355 CDD:275368 6/19 (32%)
C2H2 Zn finger 363..383 CDD:275368 10/19 (53%)
COG5048 <387..523 CDD:227381 55/135 (41%)
C2H2 Zn finger 391..411 CDD:275368 6/19 (32%)
zf-H2C2_2 403..426 CDD:290200 12/22 (55%)
C2H2 Zn finger 419..439 CDD:275368 7/19 (37%)
C2H2 Zn finger 447..467 CDD:275368 7/19 (37%)
C2H2 Zn finger 475..495 CDD:275368 7/19 (37%)
zf-H2C2_2 487..510 CDD:290200 11/22 (50%)
C2H2 Zn finger 503..523 CDD:275368 6/19 (32%)
ZNF415XP_024307363.1 KRAB 51..91 CDD:307490
COG5048 <235..497 CDD:227381 17/46 (37%)
C2H2 Zn finger 343..361 CDD:275368
COG5048 367..>662 CDD:227381 86/211 (41%)
C2H2 Zn finger 369..389 CDD:275368
C2H2 Zn finger 397..417 CDD:275368
C2H2 Zn finger 425..445 CDD:275368
C2H2 Zn finger 453..473 CDD:275368 7/19 (37%)
C2H2 Zn finger 481..501 CDD:275368 6/19 (32%)
C2H2 Zn finger 509..529 CDD:275368 10/19 (53%)
C2H2 Zn finger 537..557 CDD:275368 6/19 (32%)
C2H2 Zn finger 565..585 CDD:275368 7/19 (37%)
C2H2 Zn finger 593..613 CDD:275368 7/19 (37%)
C2H2 Zn finger 621..641 CDD:275368 7/19 (37%)
C2H2 Zn finger 649..669 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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