DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dwg and LOC549508

DIOPT Version :9

Sequence 1:	NP_477338.3	Gene:	dwg / 31265	FlyBaseID:	FBgn0000520	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	XP_031759247.1	Gene:	LOC549508 / 549508	-ID:	-	Length:	1464	Species:	Xenopus tropicalis

Alignment Length:	229	Identity:	91/229 - (39%)
Similarity:	124/229 - (54%)	Gaps:	0/229 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   304 PYVCTVCQKAFRQQCRLNQHMRSHVDEKQYECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGR 368
            |:.||.|.|.|..:..|..|.|.|..||.|.|.||||......:...|...||.:||..|:.||:
Frog  1192 PFTCTECGKCFSVKSGLKSHQRIHTGEKPYTCTECGKSFTLNSHLVRHQRIHTGIKPFACTECGK 1256

  Fly   369 FYRTTSSLAVHKRTHAEKKPYNCDQCGRGYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLR 433
            .:.....|::|||.|..:||:.|.:||:.::|.|.|..||..||||:|:.|..|.|::.....|.
Frog  1257 SFSAHHKLSLHKRVHTGEKPFTCTECGKSFSAHDKLSLHKRVHTGEKPFTCTECGKSFSAHHMLS 1321

  Fly   434 QHKISHTGKKAFTCEICGVGLSQKSGYKKHMMVHSGVKAHKCDVCGHAFTFTSNLNAHVRLHSGE 498
            .||..|||:|.|||..||....|::..:.|...|:|.|.:.|..||.:||..|||..|.::|:||
Frog  1322 LHKRVHTGEKPFTCTECGKSFRQQTHLEIHQRFHTGEKLYTCTECGKSFTVNSNLVRHQKIHTGE 1386

  Fly   499 KPFKCEVCVKAFPTKKRLASHMRVHNKESPVTAT 532
            ||:.|..|.|:|.....|..|.::|..|.|.|.|
Frog  1387 KPYTCTECGKSFTVNSHLVRHQKIHTGEKPYTCT 1420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dwg	NP_477338.3	zf-AD	14..91	CDD:214871
		COG5048	<297..451	CDD:227381	59/146 (40%)
		C2H2 Zn finger	307..327	CDD:275368	8/19 (42%)
		C2H2 Zn finger	335..355	CDD:275368	6/19 (32%)
		C2H2 Zn finger	363..383	CDD:275368	7/19 (37%)
		COG5048	<387..523	CDD:227381	55/135 (41%)
		C2H2 Zn finger	391..411	CDD:275368	8/19 (42%)
		zf-H2C2_2	403..426	CDD:290200	11/22 (50%)
		C2H2 Zn finger	419..439	CDD:275368	6/19 (32%)
		C2H2 Zn finger	447..467	CDD:275368	5/19 (26%)
		C2H2 Zn finger	475..495	CDD:275368	9/19 (47%)
		zf-H2C2_2	487..510	CDD:290200	11/22 (50%)
		C2H2 Zn finger	503..523	CDD:275368	6/19 (32%)
LOC549508	XP_031759247.1	C2H2 Zn finger	183..203	CDD:275368
		C2H2 Zn finger	210..230	CDD:275368
		C2H2 Zn finger	238..258	CDD:275368
		C2H2 Zn finger	298..318	CDD:275368
		C2H2 Zn finger	326..346	CDD:275368
		C2H2 Zn finger	354..374	CDD:275368
		C2H2 Zn finger	382..402	CDD:275368
		C2H2 Zn finger	410..430	CDD:275368
		COG5048	<429..614	CDD:227381
		C2H2 Zn finger	438..458	CDD:275368
		C2H2 Zn finger	465..485	CDD:275368
		C2H2 Zn finger	493..513	CDD:275368
		C2H2 Zn finger	521..541	CDD:275368
		COG5048	545..949	CDD:227381
		C2H2 Zn finger	549..569	CDD:275368
		C2H2 Zn finger	577..597	CDD:275368
		C2H2 Zn finger	605..625	CDD:275368
		C2H2 Zn finger	633..653	CDD:275368
		C2H2 Zn finger	661..681	CDD:275368
		C2H2 Zn finger	689..709	CDD:275368
		C2H2 Zn finger	717..737	CDD:275368
		C2H2 Zn finger	745..765	CDD:275368
		C2H2 Zn finger	773..793	CDD:275368
		C2H2 Zn finger	801..821	CDD:275368
		C2H2 Zn finger	829..849	CDD:275368
		C2H2 Zn finger	857..877	CDD:275368
		C2H2 Zn finger	885..905	CDD:275368
		C2H2 Zn finger	913..933	CDD:275368
		C2H2 Zn finger	941..961	CDD:275368
		COG5048	965..1346	CDD:227381	62/153 (41%)
		C2H2 Zn finger	969..989	CDD:275368
		C2H2 Zn finger	997..1017	CDD:275368
		C2H2 Zn finger	1025..1045	CDD:275368
		C2H2 Zn finger	1083..1103	CDD:275368
		C2H2 Zn finger	1111..1131	CDD:275368
		C2H2 Zn finger	1139..1159	CDD:275368
		C2H2 Zn finger	1167..1187	CDD:275368
		C2H2 Zn finger	1195..1215	CDD:275368	8/19 (42%)
		C2H2 Zn finger	1223..1243	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1251..1271	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1279..1299	CDD:275368	8/19 (42%)
		C2H2 Zn finger	1307..1327	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1335..1355	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1363..1383	CDD:275368	9/19 (47%)
		zf-H2C2_2	1375..1399	CDD:404364	11/23 (48%)
		C2H2 Zn finger	1391..1411	CDD:275368	6/19 (32%)
		zf-H2C2_2	1403..1427	CDD:404364	7/18 (39%)
		C2H2 Zn finger	1419..1439	CDD:275368	1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910