DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dwg and Zfp773-ps1

DIOPT Version :9

Sequence 1:	NP_477338.3	Gene:	dwg / 31265	FlyBaseID:	FBgn0000520	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	XP_017445439.1	Gene:	Zfp773-ps1 / 502292	RGDID:	1563793	Length:	424	Species:	Rattus norvegicus

Alignment Length:	457	Identity:	128/457 - (28%)
Similarity:	194/457 - (42%)	Gaps:	80/457 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 ESQTHSPNQSQQ-------HD-------QQQQAFDSTE----EYVMIEM--------LNEEQENV 142
            ::||....|..|       ||       ::.:..|.::    .:||:|:        |.....::
  Rat     7 QTQTAVAGQGAQAQGGVAFHDVAIYFLREEWRLLDDSQRRLYHHVMMEVFVLMSSSGLVPSGTDI 71

  Fly   143 ANLDEELAEEDRRIFAMTVDEEEEFLTEEVDQ-----DDELSEEEHQLAQSGDQQEEHITMESVH 202
            ..|:   :..||.|.|:      .|||..|:.     :..||..|..|         ::||....
  Rat    72 TQLE---SSGDRFIPAL------RFLTPRVEPAKIPCEQTLSTTERGL---------NVTMLPQQ 118

  Fly   203 EFQPAEVEYVTIKNEFETIVTEEDEFEVMNDS-GAHDAILDCQMIVIPAEGAIDEVIGEETLELE 266
            |...||....  :.|....||:.:..::...: .:.|..:|.:        .:..::|......:
  Rat   119 ELSSAENHLQ--RAEHRLSVTKRNRSDISEKTLQSTDNTMDSR--------TLSGLLGHHATHSD 173

  Fly   267 GDGREEHLLPEAEDVCEDEDFLEESLDSAPPTAGEALPY-VCTVCQKAFRQQCRLNQHMRSHVDE 330
            | |:                  ..|......|..|...| .|:.|.|:|..:..|.:|.|.|..|
  Rat   174 G-GQ------------------PRSTKKGKATHSEKRNYKCCSYCGKSFNCRSLLIRHRRIHTGE 219

  Fly   331 KQYECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGRFYRTTSSLAVHKRTHAEKKPYNCDQCG 395
            |.::|.||.|......:..:|:..||..||.:||.||:.::.:.||..|:|.|..:|||.|:|||
  Rat   220 KPFKCSECEKSFIQKADLNQHLKVHTGEKPFRCSKCGKKFKHSRSLVGHQRLHTGEKPYKCNQCG 284

  Fly   396 RGYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLRQHKISHTGKKAFTCEICGVGLSQKSGY 460
            ..|.....|.||.|.||||:||.|..|.|.:.:.|||..|...|||::.|.|..|.....:.|..
  Rat   285 ESYVNRSSLIRHNLVHTGEKPYKCSECGKLFKEKSSLVYHARVHTGERPFECSQCKKSFKKNSHL 349

  Fly   461 KKHMMVHSGVKAHKCDVCGHAFTFTSNLNAHVRLHSGEKPFKCEVCVKAFPTKKRLASHMRVHNK 525
            .||..|||..|..||:|||..||....|..|.|.|:.||..:|:.|.|.|..:..|:.|.:||.:
  Rat   350 VKHRKVHSRGKPFKCNVCGRFFTMRYILVKHQRFHTAEKHHECKECGKVFCYRTGLSRHRKVHAE 414

  Fly   526 ES 527
            ::
  Rat   415 KN 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dwg	NP_477338.3	zf-AD	14..91	CDD:214871
		COG5048	<297..451	CDD:227381	61/154 (40%)
		C2H2 Zn finger	307..327	CDD:275368	7/19 (37%)
		C2H2 Zn finger	335..355	CDD:275368	5/19 (26%)
		C2H2 Zn finger	363..383	CDD:275368	8/19 (42%)
		COG5048	<387..523	CDD:227381	57/135 (42%)
		C2H2 Zn finger	391..411	CDD:275368	9/19 (47%)
		zf-H2C2_2	403..426	CDD:290200	13/22 (59%)
		C2H2 Zn finger	419..439	CDD:275368	7/19 (37%)
		C2H2 Zn finger	447..467	CDD:275368	5/19 (26%)
		C2H2 Zn finger	475..495	CDD:275368	9/19 (47%)
		zf-H2C2_2	487..510	CDD:290200	9/22 (41%)
		C2H2 Zn finger	503..523	CDD:275368	6/19 (32%)
Zfp773-ps1	XP_017445439.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24384
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100