DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dwg and MAZ

DIOPT Version :9

Sequence 1:NP_477338.3 Gene:dwg / 31265 FlyBaseID:FBgn0000520 Length:592 Species:Drosophila melanogaster
Sequence 2:NP_001036004.1 Gene:MAZ / 4150 HGNCID:6914 Length:493 Species:Homo sapiens


Alignment Length:290 Identity:80/290 - (27%)
Similarity:119/290 - (41%) Gaps:74/290 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   304 PYVCTVCQKAFRQQCRLNQHMRSHVD--------------------------------------- 329
            ||:|.:|.|.|:....|.:|...|..                                       
Human   189 PYICALCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMVPLSLLSVPQLSGAGGGGGEAGA 253

  Fly   330 ----------------------EKQYECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGRFYRT 372
                                  .|.:.||.|||..:.:.:...|.|:|::.||:||.:|.:.::.
Human   254 GGGAAAVAAGGVVTTTASGKRIRKNHACEMCGKAFRDVYHLNRHKLSHSDEKPYQCPVCQQRFKR 318

  Fly   373 TSSLAVHKRTH--AEKKPYNCDQCGRGYAAFDHLRRH-KLTHTGERPYACDLCDKAYYDSSSLRQ 434
            ...::.|.|:|  |..|||||..||:.::..|||..| :..|:.|||:.|:.|:.|:.....||.
Human   319 KDRMSYHVRSHDGAVHKPYNCSHCGKSFSRPDHLNSHVRQVHSTERPFKCEKCEAAFATKDRLRA 383

  Fly   435 HKISHTGKKAFTCEICGVGLSQKSGY-KKHMMVHSGVKAHKCDVCGHAFTFTSNLNAH-VRLHSG 497
            |.:.|..|  ..|.:||..||  |.| ..||.|||....|.|::|...||..:.|..| |:.|..
Human   384 HTVRHEEK--VPCHVCGKMLS--SAYISDHMKVHSQGPHHVCELCNKGFTTAAYLRIHAVKDHGL 444

  Fly   498 EKP----FKCEVCVKAFPTKKRLASHMRVH 523
            :.|    ..|::|.....|..:||.||:.|
Human   445 QAPRADRILCKLCSVHCKTPAQLAGHMQTH 474

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dwgNP_477338.3 zf-AD 14..91 CDD:214871
COG5048 <297..451 CDD:227381 51/210 (24%)
C2H2 Zn finger 307..327 CDD:275368 6/19 (32%)
C2H2 Zn finger 335..355 CDD:275368 7/19 (37%)
C2H2 Zn finger 363..383 CDD:275368 4/19 (21%)
COG5048 <387..523 CDD:227381 52/142 (37%)
C2H2 Zn finger 391..411 CDD:275368 7/20 (35%)
zf-H2C2_2 403..426 CDD:290200 9/23 (39%)
C2H2 Zn finger 419..439 CDD:275368 6/19 (32%)
C2H2 Zn finger 447..467 CDD:275368 9/20 (45%)
C2H2 Zn finger 475..495 CDD:275368 7/20 (35%)
zf-H2C2_2 487..510 CDD:290200 7/27 (26%)
C2H2 Zn finger 503..523 CDD:275368 7/19 (37%)
MAZNP_001036004.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 59..78
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 121..146
C2H2 Zn finger 192..212 CDD:275368 6/19 (32%)
C2H2 Zn finger 281..301 CDD:275368 7/19 (37%)
SFP1 <303..360 CDD:227516 20/56 (36%)
C2H2 Zn finger 309..329 CDD:275368 4/19 (21%)
C2H2 Zn finger 339..357 CDD:275368 7/17 (41%)
C2H2 Zn finger 368..388 CDD:275368 6/19 (32%)
C2H2 Zn finger 394..413 CDD:275368 9/20 (45%)
C2H2 Zn finger 421..437 CDD:275368 5/15 (33%)
C2H2 Zn finger 454..474 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S3265
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.950

Return to query results.
Submit another query.