DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dwg and Zfp616

DIOPT Version :9

Sequence 1:	NP_477338.3	Gene:	dwg / 31265	FlyBaseID:	FBgn0000520	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_001171041.1	Gene:	Zfp616 / 327963	MGIID:	3650906	Length:	987	Species:	Mus musculus

Alignment Length:	225	Identity:	92/225 - (40%)
Similarity:	127/225 - (56%)	Gaps:	0/225 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   304 PYVCTVCQKAFRQQCRLNQHMRSHVDEKQYECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGR 368
            ||.|..|:|:|.|...|.:|.|.|..:|.|:|.||||......|.:.|...||..||::|:.||:
Mouse   564 PYKCNNCRKSFTQSSGLKRHYRIHTGDKPYKCNECGKYFTQSSNLQVHQRIHTKDKPYKCNECGK 628

  Fly   369 FYRTTSSLAVHKRTHAEKKPYNCDQCGRGYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLR 433
            ::..:|||.||.|.|...|.|.|:.||:.:.....|:||...|||.:||.|:.|.|.:..||||:
Mouse   629 YFAHSSSLKVHHRIHTRNKTYKCNNCGKSFIRSSDLKRHYRIHTGNKPYKCNDCGKYFTHSSSLK 693

  Fly   434 QHKISHTGKKAFTCEICGVGLSQKSGYKKHMMVHSGVKAHKCDVCGHAFTFTSNLNAHVRLHSGE 498
            .|...||..|.:.|..||....|.|..|:|..:|:|.|.:||:.||..|..:|:|..|.|:|:|:
Mouse   694 GHHRIHTRDKPYKCNNCGKSFRQSSSLKRHYRIHTGDKPYKCNECGKYFACSSSLKRHHRIHTGD 758

  Fly   499 KPFKCEVCVKAFPTKKRLASHMRVHNKESP 528
            ||:||..|.|.|.....|..|.|:|.|:.|
Mouse   759 KPYKCNECGKYFAQSSNLQVHQRIHTKDKP 788

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dwg	NP_477338.3	zf-AD	14..91	CDD:214871
		COG5048	<297..451	CDD:227381	59/146 (40%)
		C2H2 Zn finger	307..327	CDD:275368	8/19 (42%)
		C2H2 Zn finger	335..355	CDD:275368	7/19 (37%)
		C2H2 Zn finger	363..383	CDD:275368	9/19 (47%)
		COG5048	<387..523	CDD:227381	55/135 (41%)
		C2H2 Zn finger	391..411	CDD:275368	6/19 (32%)
		zf-H2C2_2	403..426	CDD:290200	11/22 (50%)
		C2H2 Zn finger	419..439	CDD:275368	8/19 (42%)
		C2H2 Zn finger	447..467	CDD:275368	7/19 (37%)
		C2H2 Zn finger	475..495	CDD:275368	8/19 (42%)
		zf-H2C2_2	487..510	CDD:290200	11/22 (50%)
		C2H2 Zn finger	503..523	CDD:275368	7/19 (37%)
Zfp616	NP_001171041.1	C2H2 Zn finger	426..446	CDD:275368
		C2H2 Zn finger	454..474	CDD:275368
		C2H2 Zn finger	483..502	CDD:275368
		COG5048	506..914	CDD:227381	92/225 (41%)
		C2H2 Zn finger	511..531	CDD:275368
		C2H2 Zn finger	539..559	CDD:275368
		zf-H2C2_2	551..576	CDD:290200	6/11 (55%)
		C2H2 Zn finger	567..587	CDD:275368	8/19 (42%)
		zf-H2C2_2	580..604	CDD:290200	11/23 (48%)
		C2H2 Zn finger	595..615	CDD:275368	7/19 (37%)
		zf-H2C2_2	607..632	CDD:290200	9/24 (38%)
		C2H2 Zn finger	623..643	CDD:275368	9/19 (47%)
		zf-C2H2	649..671	CDD:278523	7/21 (33%)
		C2H2 Zn finger	651..671	CDD:275368	6/19 (32%)
		zf-H2C2_2	663..688	CDD:290200	11/24 (46%)
		C2H2 Zn finger	679..699	CDD:275368	8/19 (42%)
		zf-C2H2	705..727	CDD:278523	7/21 (33%)
		C2H2 Zn finger	707..727	CDD:275368	7/19 (37%)
		zf-H2C2_2	719..744	CDD:290200	10/24 (42%)
		C2H2 Zn finger	735..755	CDD:275368	8/19 (42%)
		zf-H2C2_2	747..772	CDD:290200	12/24 (50%)
		C2H2 Zn finger	763..783	CDD:275368	7/19 (37%)
		zf-H2C2_2	775..800	CDD:290200	6/14 (43%)
		C2H2 Zn finger	791..811	CDD:275368
		zf-H2C2_2	803..828	CDD:290200
		C2H2 Zn finger	819..839	CDD:275368
		zf-H2C2_2	831..856	CDD:290200
		C2H2 Zn finger	847..867	CDD:275368
		zf-H2C2_2	859..884	CDD:290200
		C2H2 Zn finger	875..895	CDD:275368
		zf-H2C2_2	887..912	CDD:290200
		C2H2 Zn finger	903..923	CDD:275368
		zf-H2C2_2	915..940	CDD:290200
		C2H2 Zn finger	931..951	CDD:275368
		zf-H2C2_2	943..968	CDD:290200
		C2H2 Zn finger	959..979	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	51	1.000	Domainoid score	I11471
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910