DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dwg and Vezf1

DIOPT Version :9

Sequence 1:NP_477338.3 Gene:dwg / 31265 FlyBaseID:FBgn0000520 Length:592 Species:Drosophila melanogaster
Sequence 2:XP_036012519.1 Gene:Vezf1 / 22344 MGIID:1313291 Length:556 Species:Mus musculus


Alignment Length:378 Identity:94/378 - (24%)
Similarity:143/378 - (37%) Gaps:102/378 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   244 QMIVIPAEGAID----EVIGE--------------------ETLELEGDGREEHLLPEAEDVCED 284
            |.|::.|.|.|.    ..|||                    |....:....:..|||......|.
Mouse     5 QKIILSASGPIPVELIRGIGEFKITHCVIWLVLLRHVSNAHEASHHQQQAAQNSLLPLLSSAVEP 69

  Fly   285 EDF-------LEESLDSAPPTAGEAL---------PYVCTVCQKAFRQQCRLNQHMRSHVDEKQY 333
            .|.       :.:...:||.|..:|:         .:|||.|.||||.    :.|:|.|      
Mouse    70 PDQKPLLPIPITQKPQAAPETLKDAIGIKKEKPKTSFVCTYCSKAFRD----SYHLRRH------ 124

  Fly   334 ECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGRFYRT-------------------------- 372
              :.|...:|.:...|:   |.|.|.|...:|.|...||                          
Mouse   125 --QSCHTGIKLVSRAKK---TPTTVVPLISTIAGDSSRTSLVSTIAGILSTVTTSSSGTNPSSSA 184

  Fly   373 -TSSL----AVHKRTHAEKKPYNCDQCGRGYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSL 432
             |:|:    :|.|.:...||.:.|:.||:.:....||.||||:|:.|:|:.|.:|::.:.....:
Mouse   185 STTSMPVPQSVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRM 249

  Fly   433 RQHKISHTG--KKAFTCEICGVGLSQK---SGYKKHMMVHSGVKAHKC------DVCGHAFTFTS 486
            ..|..||.|  .|.:||.:||.|.|:.   |.:.||  |||..:..||      ..|..||....
Mouse   250 TYHVRSHEGGITKPYTCSVCGKGFSRPDHLSCHVKH--VHSTERPFKCQFSSLMQTCTAAFATKD 312

  Fly   487 NLNAHVRLHSGEKPFKCEVCVKAFPTKKRLASHMRVHNKESPVTATVAVQSIN 539
            .|..|:..|.|:  ..|.:|.|.. :...:.||::.|.:...:......|.|:
Mouse   313 RLRTHMVRHEGK--VSCNICGKLL-SAAYITSHLKTHGQSQSINCNTCKQGIS 362

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dwgNP_477338.3 zf-AD 14..91 CDD:214871
COG5048 <297..451 CDD:227381 51/195 (26%)
C2H2 Zn finger 307..327 CDD:275368 9/19 (47%)
C2H2 Zn finger 335..355 CDD:275368 3/19 (16%)
C2H2 Zn finger 363..383 CDD:275368 8/50 (16%)
COG5048 <387..523 CDD:227381 46/146 (32%)
C2H2 Zn finger 391..411 CDD:275368 9/19 (47%)
zf-H2C2_2 403..426 CDD:290200 11/22 (50%)
C2H2 Zn finger 419..439 CDD:275368 3/19 (16%)
C2H2 Zn finger 447..467 CDD:275368 8/22 (36%)
C2H2 Zn finger 475..495 CDD:275368 6/25 (24%)
zf-H2C2_2 487..510 CDD:290200 7/22 (32%)
C2H2 Zn finger 503..523 CDD:275368 5/19 (26%)
Vezf1XP_036012519.1 zf-C2H2 106..125 CDD:395048 11/30 (37%)
C2H2 Zn finger 108..128 CDD:275368 10/31 (32%)
zf-C2H2 206..228 CDD:395048 9/21 (43%)
C2H2 Zn finger 208..228 CDD:275368 9/19 (47%)
SFP1 <230..287 CDD:227516 18/58 (31%)
C2H2 Zn finger 236..256 CDD:275368 3/19 (16%)
C2H2 Zn finger 266..284 CDD:275368 6/17 (35%)
C2H2 Zn finger 295..321 CDD:275368 6/25 (24%)
motB <415..532 CDD:183756
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.