DRSC/TRiP Functional Genomics Resources

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Protein Alignment dwg and ZUP1

DIOPT Version :9

Sequence 1:NP_477338.3 Gene:dwg / 31265 FlyBaseID:FBgn0000520 Length:592 Species:Drosophila melanogaster
Sequence 2:NP_001348118.1 Gene:ZUP1 / 221302 HGNCID:21224 Length:578 Species:Homo sapiens


Alignment Length:303 Identity:61/303 - (20%)
Similarity:102/303 - (33%) Gaps:83/303 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   199 ESVHEFQPAEVEYVTIKNEFETIVTEEDEFEVMNDSGAHDAILDCQMIVIPA----------EGA 253
            |.....:.|..|..|::..||.|.|    .:........|..|.|.|.|..:          :.:
Human    43 EMCFHIETAHFEQNTLERNFERINT----VQYGTSDNKKDNTLQCGMEVNSSILSGCASNHPKNS 103

  Fly   254 IDEVIGEETLELEGDGREEHLLPEAEDVCEDEDFLEESLDSAPPTAGEALPYVCTVCQKAFRQQC 318
            ...:..:.||:.||.        .:|::.|...||                       |:..:|.
Human   104 AQNLTKDSTLKHEGF--------YSENLTESRKFL-----------------------KSREKQS 137

  Fly   319 RLNQHMRSHVDEKQY---ECEECGKRLKHLRNYKEHMLT-HTNV---------KP-HQCSICGRF 369
            .|.: ::..|.|..|   ||..|||..:|..:.:.|:.| |.|:         :| :.|.:||..
Human   138 SLTE-IKGSVYETTYSPPECPFCGKIEEHSEDMETHVKTKHANLLDIPLEDCDQPLYDCPMCGLI 201

  Fly   370 YRTTSSLAVHKRTHAEKKPYNCDQCG--RGYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSL 432
            ......|..|...|.|:   |..|.|  |...:.|....|:|....:|....:...:...:...|
Human   202 CTNYHILQEHVDLHLEE---NSFQQGMDRVQCSGDLQLAHQLQQEEDRKRRSEESRQEIEEFQKL 263

  Fly   433 -RQHKISHTGKKAFTCEICGVGLSQKSGYKKHMMVHSGVKAHK 474
             ||:                 ||....|||:..:.:..::.::
Human   264 QRQY-----------------GLDNSGGYKQQQLRNMEIEVNR 289

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dwgNP_477338.3 zf-AD 14..91 CDD:214871
COG5048 <297..451 CDD:227381 35/170 (21%)
C2H2 Zn finger 307..327 CDD:275368 3/19 (16%)
C2H2 Zn finger 335..355 CDD:275368 7/20 (35%)
C2H2 Zn finger 363..383 CDD:275368 5/19 (26%)
COG5048 <387..523 CDD:227381 16/91 (18%)
C2H2 Zn finger 391..411 CDD:275368 6/21 (29%)
zf-H2C2_2 403..426 CDD:290200 3/22 (14%)
C2H2 Zn finger 419..439 CDD:275368 3/20 (15%)
C2H2 Zn finger 447..467 CDD:275368 5/19 (26%)
C2H2 Zn finger 475..495 CDD:275368 61/303 (20%)
zf-H2C2_2 487..510 CDD:290200
C2H2 Zn finger 503..523 CDD:275368
ZUP1NP_001348118.1 MIU. /evidence=ECO:0000305|PubMed:29476094, ECO:0000305|PubMed:29576527 226..248 5/21 (24%)
zUBD/ZHA. /evidence=ECO:0000305|PubMed:29476094, ECO:0000305|PubMed:29576527 249..274 5/41 (12%)
Peptidase_C78 336..551 CDD:311731
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165149925
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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