Protein Alignment dwg and Zfp719

DIOPT Version :10

• Sequence 1: NP_477338.3
• Gene: dwg / 31265
• FlyBaseID: FBgn0000520
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_766070.1
• Gene: Zfp719 / 210105
• MGIID: 2444708
• Length: 735
• Species: Mus musculus
• Alignment Length: 582
• Identity: 154/582 - (26%)
• Similarity: 236/582 - (40%)
• Gaps: 124/582 - (21%)

  Fly    36 EGSTTLASMLNYC---TGLSFEPQDGAAMPQHICLHCLQLLEQAFNFKRMVIDSDELLRLGLDEA 97
            |.:..:.:.:|:|   ..|..|.|||             |.|:..:|..:.:|..:.....||.|
Mouse    18 ETTEDMPTDMNFCQMPQQLGAEEQDG-------------LCERLVSFDDVTVDFSQEEWQHLDSA 69

  Fly    98 RCSSFHE------SQTHSPNQSQQHDQQQQAF-------DSTEEYV--------MIEMLNEEQEN 141
            :...:.:      |...|..:.|...|.||.|       |:..|..        ::|.|.:|.:.
Mouse    70 QRRLYQDVMLEIYSHLLSVGKLQLDTQHQQIFVKASFLSDAASEVTKHGSIYCSVLEKLWQEGDP 134

  Fly   142 VANLDEELAEEDRRIFAMT--VDEEEEFLTEEVDQDDELSEEEHQLAQSGDQQEEH-ITMESVHE 203
            .|..|::     .|:..::  ..:.::.||.....|.|.:||...|       |.| |:.:.|..
Mouse   135 AAKTDQQ-----SRVLPVSPGAFQNQKILTIGSAWDYEETEESTLL-------EPHLISTQYVPP 187

  Fly   204 FQPAEVEYVTIKNEFETIVTEEDEFEVMNDSGAHDAILDCQMIVIP-------AEGAIDEVIG-- 259
            ...::.:..||| :...|:..:..|...:.:|         :..:|       .|.....::.
Mouse   188 RANSDSQSNTIK-QLNDIIGSDQFFTQASSNG---------VCTVPHQTEKPYTESQFGNIVSLN 242

  Fly   260 -----------EETLELEGDGR---------EEHLLPEAED--VCE--DEDFLEES-LDSAPPTA 299
                       ::.:|..|.|:         ::.:....|.  :|.  .:.||.:| |.|...|.
Mouse   243 PPLMDHEINFQDKPVEYTGCGKVFTGETAFCQQQITNSMETSFICHTCGKTFLHKSKLTSHSETP 307

  Fly   300 GEALPYVCTVCQKAFRQQCRLNQHMRSHVDEKQYECEECGKRLKHLRNYKEHMLTHTNVKPHQCS 364
            .|..||.|..|.|:.|....|.........||.|||..|||...:..:.|.|:.|||..||:.||
Mouse   308 REETPYECPDCAKSLRGTTSLQVLRGVQTKEKPYECHVCGKSFSYTSHLKVHLRTHTGEKPYACS 372

  Fly   365 ICGRFYRTTSSLAVHKRTHAEKKPYNCDQCGRGYAAFDHLRRHKLTHTGERPYACDLCDKAYYDS 429
            .||:.:...|.|.:|:|.|..:|||.|..||:.:.....|.:|...||||:||.|..|.|::...
Mouse   373 DCGKAFSQKSVLTIHQRIHTGEKPYTCSDCGKMFVCASDLTKHCRFHTGEKPYECPDCGKSFSIK 437

  Fly   430 SSLRQH--------------------KIS--------HTGKKAFTCEICGVGLSQKSGYKKHMMV 466
            |:|..|                    |||        ||.:::|.|..||:..||||....|..:
Mouse   438 SNLLAHHRIHTSEGPYKCFHCGESFRKISQLKVHHQIHTDRRSFVCSDCGMAFSQKSVLTTHQRI 502

  Fly   467 HSGVKAHKCDVCGHAFTFTSNLNAHVRLHSGEKPFKCEVCVKAFPTKKRLASHMRVHNKESP 528
            |||.|.:.|..||..|.:.|:|..|.|.|:||||:||..|.|::..|..|..|.|:|..|.|
Mouse   503 HSGEKCYPCSDCGKLFLYASDLKKHCRFHTGEKPYKCHDCGKSYSVKSHLHVHHRIHTGERP 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dwg	NP_477338.3	zf-AD	14..91	CDD:214871	12/57 (21%)
		COG5048	<297..451	CDD:227381	60/181 (33%)
		C2H2 Zn finger	307..327	CDD:275368	5/19 (26%)
		C2H2 Zn finger	335..355	CDD:275368	6/19 (32%)
		C2H2 Zn finger	363..383	CDD:275368	8/19 (42%)
		COG5048	<387..523	CDD:227381	59/163 (36%)
		C2H2 Zn finger	391..411	CDD:275368	5/19 (26%)
		C2H2 Zn finger	419..439	CDD:275368	9/47 (19%)
		C2H2 Zn finger	447..467	CDD:275368	8/19 (42%)
		C2H2 Zn finger	475..495	CDD:275368	8/19 (42%)
		C2H2 Zn finger	503..523	CDD:275368	7/19 (37%)
Zfp719	NP_766070.1	KRAB	48..89	CDD:460171	7/40 (18%)
		C2H2 Zn finger	287..307	CDD:275368	6/19 (32%)
		C2H2 Zn finger	315..335	CDD:275368	5/19 (26%)
		COG5048	335..708	CDD:227381	86/230 (37%)
		C2H2 Zn finger	343..363	CDD:275368	6/19 (32%)
		C2H2 Zn finger	371..391	CDD:275368	8/19 (42%)
		C2H2 Zn finger	399..419	CDD:275368	5/19 (26%)
		C2H2 Zn finger	427..447	CDD:275368	6/19 (32%)
		C2H2 Zn finger	455..475	CDD:275368	3/19 (16%)
		C2H2 Zn finger	483..503	CDD:275368	8/19 (42%)
		C2H2 Zn finger	511..531	CDD:275368	8/19 (42%)
		C2H2 Zn finger	539..559	CDD:275368	7/19 (37%)
		C2H2 Zn finger	567..587	CDD:275368
		C2H2 Zn finger	595..615	CDD:275368
		C2H2 Zn finger	623..643	CDD:275368
		C2H2 Zn finger	651..671	CDD:275368
		C2H2 Zn finger	679..699	CDD:275368