DRSC/TRiP Functional Genomics Resources

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Protein Alignment dwg and lin-29

DIOPT Version :9

Sequence 1:NP_477338.3 Gene:dwg / 31265 FlyBaseID:FBgn0000520 Length:592 Species:Drosophila melanogaster
Sequence 2:NP_496545.1 Gene:lin-29 / 174830 WormBaseID:WBGene00003015 Length:459 Species:Caenorhabditis elegans


Alignment Length:314 Identity:85/314 - (27%)
Similarity:123/314 - (39%) Gaps:67/314 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   301 EALPYVCTVCQKAFRQQCRLNQHMRSHVDEKQY-ECEECGKRLKHLRNYKEHMLTHTNVKPHQCS 364
            ||.||.||.|.|||.....|:||||.|:..|.: .|..|||:...|.:.::|:.|||..||::|.
 Worm   147 EAKPYKCTQCVKAFANSSYLSQHMRIHLGIKPFGPCNYCGKKFTQLSHLQQHIRTHTGEKPYKCK 211

  Fly   365 I--CGRFYRTTSSLAVHKRTHAEKKPYNCDQCGRGYAAF-------DHLRRHKLT-HTGERPYAC 419
            .  |.:.:...|:|..|.|.|...||:.|:.|   |..|       ||:.:||.: |.  :.:.|
 Worm   212 FTGCDKAFSQLSNLQSHSRCHQTDKPFKCNSC---YKCFTDEQSLLDHIPKHKESKHL--KIHIC 271

  Fly   420 DLCDKAYYDSSSLRQHKISHTGK-KA--FTCEICGVGLSQKSGYKKHMMVHSGVKAHKCDVCGHA 481
            ..|.|:|...:.|::|...|..: ||  |..::........|....:.|...|..||.    ..:
 Worm   272 PFCGKSYTQQTYLQKHMTKHADRSKASNFGNDVVPADPFDPSLLSWNPMQGMGDNAHD----SSS 332

  Fly   482 F---TFTSNLNAHVRLHSGEKPFKCEVCVKAF---------------PTKKR------------- 515
            |   :.|....|:..:.|....:.......||               ||..:             
 Worm   333 FNISSLTDQFAANTMIGSQSTNYNPAFQNSAFSQLFNIRNNRYLSEYPTSTKNGERAPGFNMITP 397

  Fly   516 LASHMRVHNKESPVTATV-----AVQSINPPSRQAGAEGATGGGATGGSPTGGG 564
            |.:..|.:...|..||.|     ||.|..|.|        |...:.|.|.:.||
 Worm   398 LENIQRYNGSSSSATAVVTATGSAVVSSTPSS--------TSSSSAGSSSSQGG 443

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dwgNP_477338.3 zf-AD 14..91 CDD:214871
COG5048 <297..451 CDD:227381 56/163 (34%)
C2H2 Zn finger 307..327 CDD:275368 11/19 (58%)
C2H2 Zn finger 335..355 CDD:275368 6/19 (32%)
C2H2 Zn finger 363..383 CDD:275368 6/21 (29%)
COG5048 <387..523 CDD:227381 36/177 (20%)
C2H2 Zn finger 391..411 CDD:275368 8/27 (30%)
zf-H2C2_2 403..426 CDD:290200 7/23 (30%)
C2H2 Zn finger 419..439 CDD:275368 6/19 (32%)
C2H2 Zn finger 447..467 CDD:275368 2/19 (11%)
C2H2 Zn finger 475..495 CDD:275368 3/22 (14%)
zf-H2C2_2 487..510 CDD:290200 2/22 (9%)
C2H2 Zn finger 503..523 CDD:275368 6/47 (13%)
lin-29NP_496545.1 zf-C2H2 151..173 CDD:278523 12/21 (57%)
C2H2 Zn finger 153..173 CDD:275368 11/19 (58%)
zf-H2C2_2 165..191 CDD:290200 11/25 (44%)
zf-C2H2_8 181..265 CDD:292531 28/86 (33%)
C2H2 Zn finger 182..202 CDD:275368 6/19 (32%)
zf-C2H2 182..202 CDD:278523 6/19 (32%)
zf-H2C2_2 194..221 CDD:290200 8/26 (31%)
C2H2 Zn finger 210..232 CDD:275368 6/21 (29%)
zf-H2C2_2 224..248 CDD:290200 9/26 (35%)
C2H2 Zn finger 240..269 CDD:275368 9/33 (27%)
zf-C2H2 269..291 CDD:278523 6/21 (29%)
C2H2 Zn finger 271..291 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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