DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dwg and Maz

DIOPT Version :9

Sequence 1:NP_477338.3 Gene:dwg / 31265 FlyBaseID:FBgn0000520 Length:592 Species:Drosophila melanogaster
Sequence 2:NP_001359451.1 Gene:Maz / 17188 MGIID:1338823 Length:493 Species:Mus musculus


Alignment Length:333 Identity:84/333 - (25%)
Similarity:126/333 - (37%) Gaps:106/333 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   293 DSAPPTAGEAL--------------------------------PYVCTVCQKAFRQQCRLNQHMR 325
            ::|||.|...:                                ||:|.:|.|.|:....|.:|..
Mouse   146 EAAPPAAAATIAAAAATAVVAPTSTVAVAPVASVLEKKTKSKGPYICALCAKEFKNGYNLRRHEA 210

  Fly   326 SHVD------------------------------------------------------------- 329
            .|..                                                             
Mouse   211 IHTGAKAGRVPSGAMKMPTMVPLSLLSVPQLSGASGGGGEAGAGGGTAAVAAGGVVTTTASGKRI 275

  Fly   330 EKQYECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGRFYRTTSSLAVHKRTH--AEKKPYNCD 392
            .|.:.||.|||..:.:.:...|.|:|::.||:||.:|.:.::....::.|.|:|  |..|||||.
Mouse   276 RKNHACEMCGKAFRDVYHLNRHKLSHSDEKPYQCPVCQQRFKRKDRMSYHVRSHDGAVHKPYNCS 340

  Fly   393 QCGRGYAAFDHLRRH-KLTHTGERPYACDLCDKAYYDSSSLRQHKISHTGKKAFTCEICGVGLSQ 456
            .||:.::..|||..| :..|:.|||:.|:.|:.|:.....||.|.:.|..|  ..|.:||..|| 
Mouse   341 HCGKSFSRPDHLNSHVRQVHSTERPFKCEKCEAAFATKDRLRAHTVRHEEK--VPCHVCGKMLS- 402

  Fly   457 KSGY-KKHMMVHSGVKAHKCDVCGHAFTFTSNLNAH-VRLHSGEKP----FKCEVCVKAFPTKKR 515
             |.| ..||.|||....|.|::|...||..:.|..| |:.|..:.|    ..|::|.....|..:
Mouse   403 -SAYISDHMKVHSQGPHHVCELCNKGFTTAAYLRIHAVKDHGLQAPRADRILCKLCSVHCKTPAQ 466

  Fly   516 LASHMRVH 523
            ||.||:.|
Mouse   467 LAGHMQTH 474

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dwgNP_477338.3 zf-AD 14..91 CDD:214871
COG5048 <297..451 CDD:227381 53/249 (21%)
C2H2 Zn finger 307..327 CDD:275368 6/19 (32%)
C2H2 Zn finger 335..355 CDD:275368 7/19 (37%)
C2H2 Zn finger 363..383 CDD:275368 4/19 (21%)
COG5048 <387..523 CDD:227381 52/142 (37%)
C2H2 Zn finger 391..411 CDD:275368 7/20 (35%)
zf-H2C2_2 403..426 CDD:290200 9/23 (39%)
C2H2 Zn finger 419..439 CDD:275368 6/19 (32%)
C2H2 Zn finger 447..467 CDD:275368 9/20 (45%)
C2H2 Zn finger 475..495 CDD:275368 7/20 (35%)
zf-H2C2_2 487..510 CDD:290200 7/27 (26%)
C2H2 Zn finger 503..523 CDD:275368 7/19 (37%)
MazNP_001359451.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 59..78
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 121..144
C2H2 Zn finger 192..212 CDD:275368 6/19 (32%)
C2H2 Zn finger 281..301 CDD:275368 7/19 (37%)
SFP1 <303..360 CDD:227516 20/56 (36%)
C2H2 Zn finger 309..329 CDD:275368 4/19 (21%)
C2H2 Zn finger 339..357 CDD:275368 7/17 (41%)
C2H2 Zn finger 368..388 CDD:275368 6/19 (32%)
C2H2 Zn finger 394..413 CDD:275368 9/20 (45%)
C2H2 Zn finger 421..437 CDD:275368 5/15 (33%)
C2H2 Zn finger 454..474 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S3265
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.950

Return to query results.
Submit another query.