DRSC/TRiP Functional Genomics Resources

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Protein Alignment dwg and ZNF513

DIOPT Version :9

Sequence 1:NP_477338.3 Gene:dwg / 31265 FlyBaseID:FBgn0000520 Length:592 Species:Drosophila melanogaster
Sequence 2:NP_653232.3 Gene:ZNF513 / 130557 HGNCID:26498 Length:541 Species:Homo sapiens


Alignment Length:535 Identity:112/535 - (20%)
Similarity:164/535 - (30%) Gaps:235/535 - (43%)


- Green bases have known domain annotations that are detailed below.


  Fly   236 AHDAILDCQMIVIPAEGAIDEVIG-----------------EETLELEGDGREEHLLPEAED--- 280
            :|...:.|:.:.:..|.::||..|                 ||..|.||||..:.|:....|   
Human     7 SHPQPVKCEGVKVDTEDSLDEGPGALVLESDLLLGQDLEFEEEEEEEEGDGNSDQLMGFERDSEG 71

  Fly   281 ------------VCED----------EDFLEE-----------------SLDSAP---------- 296
                        :.:|          |..:||                 .|...|          
Human    72 DSLGARPGLPYGLSDDESGGGRALSAESEVEEPARGPGEARGERPGPACQLCGGPTGEGPCCGAG 136

  Fly   297 -PTAGEALP----YVCTVCQKAFRQQCRLNQHMRSHVDEKQYECEECGKRLKHLRNYKEHMLTHT 356
             |..|..||    |.|.:|.........|.:||::|..||.:.|..|......|.|...|..|||
Human   137 GPGGGPLLPPRLLYSCRLCTFVSHYSSHLKRHMQTHSGEKPFRCGRCPYASAQLVNLTRHTRTHT 201

  Fly   357 NVKPHQCSICGRFYRTTSSLAVHKRTHA--------------------------EKK-------- 387
            ..||::|..|.....:..:|..|:||||                          |::        
Human   202 GEKPYRCPHCPFACSSLGNLRRHQRTHAGPPTPPCPTCGFRCCTPRPARPPSPTEQEGAVPRRPE 266

  Fly   388 ----------------------------------------------PYNCDQCG----------- 395
                                                          |:.|..||           
Human   267 DALLLPDLSLHVPPGGASFLPDCGQLRGEGEGLCGTGSEPLPELLFPWTCRGCGQELEEGEGSRL 331

  Fly   396 --------------------------RGYAAF---------DHLRRHKLTHTGERPYACDLCDKA 425
                                      :|:|..         :||.||..||:||:|:.|..|..|
Human   332 GAAMCGRCMRGEAGGGASGGPQGPSDKGFACSLCPFATHYPNHLARHMKTHSGEKPFRCARCPYA 396

  Fly   426 YYDSSSLRQHKISHTGKKAFTCEICGVGLSQKSGYKKHMMVHSGVKAHKCDVCGHAFTFTSNLNA 490
            .....:|::|:..|||:|.:.|.:|.......:..|:|..:|||.|..:|.:|.::...:.||..
Human   397 SAHLDNLKRHQRVHTGEKPYKCPLCPYACGNLANLKRHGRIHSGDKPFRCSLCNYSCNQSMNLKR 461

  Fly   491 HVRLHSGEKPFKCEVCVKAFPT-----KKRLASHMRVHNKESPVTATVAVQSINPPSRQAGAEGA 550
            |:..|:|||||:|..|  |:.|     .||   |.:||                         |.
Human   462 HMLRHTGEKPFRCATC--AYTTGHWDNYKR---HQKVH-------------------------GH 496

  Fly   551 TGGGATGGSPTGGGA 565
            .|.|..|.|.:.|.|
Human   497 GGAGGPGLSASEGWA 511

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dwgNP_477338.3 zf-AD 14..91 CDD:214871
COG5048 <297..451 CDD:227381 57/283 (20%)
C2H2 Zn finger 307..327 CDD:275368 5/19 (26%)
C2H2 Zn finger 335..355 CDD:275368 5/19 (26%)
C2H2 Zn finger 363..383 CDD:275368 5/19 (26%)
COG5048 <387..523 CDD:227381 50/240 (21%)
C2H2 Zn finger 391..411 CDD:275368 9/65 (14%)
zf-H2C2_2 403..426 CDD:290200 11/22 (50%)
C2H2 Zn finger 419..439 CDD:275368 5/19 (26%)
C2H2 Zn finger 447..467 CDD:275368 4/19 (21%)
C2H2 Zn finger 475..495 CDD:275368 5/19 (26%)
zf-H2C2_2 487..510 CDD:290200 11/22 (50%)
C2H2 Zn finger 503..523 CDD:275368 7/24 (29%)
ZNF513NP_653232.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..118 19/110 (17%)
C2H2 Zn finger 152..172 CDD:275368 5/19 (26%)
COG5048 176..>228 CDD:227381 16/51 (31%)
C2H2 Zn finger 180..200 CDD:275368 5/19 (26%)
zf-H2C2_2 192..217 CDD:316026 9/24 (38%)
C2H2 Zn finger 208..228 CDD:275368 5/19 (26%)
C2H2 Zn finger 362..382 CDD:275368 4/19 (21%)
COG5048 <372..>450 CDD:227381 27/77 (35%)
C2H2 Zn finger 390..410 CDD:275368 5/19 (26%)
COG5048 414..>487 CDD:227381 24/74 (32%)
C2H2 Zn finger 418..438 CDD:275368 4/19 (21%)
C2H2 Zn finger 446..466 CDD:275368 5/19 (26%)
C2H2 Zn finger 474..493 CDD:275368 7/23 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 492..541 9/45 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165149931
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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