DRSC/TRiP Functional Genomics Resources

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Protein Alignment dwg and AgaP_AGAP001132

DIOPT Version :9

Sequence 1:NP_477338.3 Gene:dwg / 31265 FlyBaseID:FBgn0000520 Length:592 Species:Drosophila melanogaster
Sequence 2:XP_322029.5 Gene:AgaP_AGAP001132 / 1282034 VectorBaseID:AGAP001132 Length:653 Species:Anopheles gambiae


Alignment Length:579 Identity:152/579 - (26%)
Similarity:252/579 - (43%) Gaps:97/579 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 EVVVLN--CRTCTRACKLHKPLQEEID-LGSEGSTTLASMLNYCTGLSFEPQDGAAMPQHICLHC 69
            :::.|:  ||||.        ::.|.| |.......||..:..||.::....||  :|.|||..|
Mosquito    40 KIIYLDRVCRTCL--------VEREKDQLKDLFEFCLADTIMSCTRITVAESDG--LPCHICTDC 94

  Fly    70 LQLLEQAFNFKRMVIDSDELLRLGLDEARCSSFHESQT------------HSPNQSQQ-----HD 117
            ...||::|||::|...||..:|..|:|:.... .:|:|            |..:::..     .:
Mosquito    95 CLELERSFNFQQMTKASDATIRSLLEESVVIK-QDSETKYEVLNVVVTDLHGNSETSAVVVPIEE 158

  Fly   118 QQQQAFDSTEEYVMIEMLNEEQENVANL-DEELAEEDRRIFAMTVDEEEE--------FLTEEVD 173
            .:.|..:|.:.    .::::..|:..|: ..:|...|....|..::|..:        .::....
Mosquito   159 LRFQLLNSNDN----TLVDDRTEDAVNIPPSDLTANDTSPKATAIEENLQTVNPTTALTMSTATP 219

  Fly   174 QDDELSEEEHQLAQSGDQQEEHITMESVHEFQPAEVEYVTIKNEFETIVTEEDEFEVMNDSGAHD 238
            ..|:|:.::...|:|   ..|.||:.             |:|.|....::.....::..:....|
Mosquito   220 APDKLTSDQPSTAKS---LRESITLR-------------TLKQELSEFISGNSSADISKNVEIVD 268

  Fly   239 AILDCQMIVIPAEGAIDEVIGEETLELEGDGREEHLLPEAEDVCEDEDFLEE---------SLDS 294
            ..:|.::|.:   ..:.:.:.||.:::     .|:.|..:....::|:.||:         |:::
Mosquito   269 ENVDDELIHV---DYLKDALTEEYIQI-----MENQLASSVPCSKEEEQLEQEHLNNLIHASMEA 325

  Fly   295 APP-------TAGEALPYVCTVCQKAFRQQCRLNQHMRSHVD----EKQYECEECGKRLKHLRNY 348
            ..|       .|.|.....|.:|...|.:: ||   .|.|||    ||::||:.|.::.......
Mosquito   326 EEPRERPKSEDANEINTMYCKICDVQFSKR-RL---YRKHVDRKHSEKRFECQLCSRKFAEKSVL 386

  Fly   349 KEHMLTHTNVKPHQCSIC-GRFYRTTSSLAVHKRTHAEKKPYNCDQCGRGYAAFDHLRRHKLTHT 412
            |.|||.||..|.|.|.:| .|||. .:.|.||.|.|:..:||.|:.|.:.:|....|..|:..|:
Mosquito   387 KNHMLRHTGEKSHVCDVCDARFYE-KALLNVHMRRHSGSRPYGCELCDKRFATRSMLNTHQKVHS 450

  Fly   413 GERPYACDLCDKAYYDSSSLRQHKISHTGKKAFTCEICGVGLSQKSGYKKHMMVHSGVKAHKCDV 477
            ..||:.|::|.|.:..|..|:.|...||.:|.|.|..|....:|......|:..|||.|.:.|.:
Mosquito   451 DPRPHVCNVCQKGFKLSWQLKAHGRIHTNEKPFECPYCQKRFNQNGNLAVHIRTHSGEKPYVCKI 515

  Fly   478 CGHAFTFTSNLNAHVRLHSGEKPFK---CEVCVKAFPTKKRLASHMRVHNKESPVTATV 533
            |..|:.....|..|.|.|:||:..|   |.||.||.||...|..|||:|.||.|...||
Mosquito   516 CEKAYPSQGELQCHTRQHTGEEKVKKVVCTVCSKALPTNHDLLIHMRIHTKEKPYGCTV 574

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dwgNP_477338.3 zf-AD 14..91 CDD:214871 26/77 (34%)
COG5048 <297..451 CDD:227381 56/165 (34%)
C2H2 Zn finger 307..327 CDD:275368 6/19 (32%)
C2H2 Zn finger 335..355 CDD:275368 6/19 (32%)
C2H2 Zn finger 363..383 CDD:275368 9/20 (45%)
COG5048 <387..523 CDD:227381 49/138 (36%)
C2H2 Zn finger 391..411 CDD:275368 5/19 (26%)
zf-H2C2_2 403..426 CDD:290200 8/22 (36%)
C2H2 Zn finger 419..439 CDD:275368 6/19 (32%)
C2H2 Zn finger 447..467 CDD:275368 4/19 (21%)
C2H2 Zn finger 475..495 CDD:275368 6/19 (32%)
zf-H2C2_2 487..510 CDD:290200 11/25 (44%)
C2H2 Zn finger 503..523 CDD:275368 11/19 (58%)
AgaP_AGAP001132XP_322029.5 zf-AD 47..117 CDD:214871 26/79 (33%)
C2H2 Zn finger 345..366 CDD:275368 9/24 (38%)
C2H2 Zn finger 373..393 CDD:275368 6/19 (32%)
zf-H2C2_2 386..408 CDD:290200 10/21 (48%)
C2H2 Zn finger 401..421 CDD:275368 9/20 (45%)
C2H2 Zn finger 429..449 CDD:275368 5/19 (26%)
C2H2 Zn finger 457..477 CDD:275368 6/19 (32%)
zf-H2C2_2 470..494 CDD:290200 8/23 (35%)
zf-C2H2 483..505 CDD:278523 5/21 (24%)
C2H2 Zn finger 485..505 CDD:275368 4/19 (21%)
zf-H2C2_2 497..520 CDD:290200 7/22 (32%)
C2H2 Zn finger 513..533 CDD:275368 6/19 (32%)
C2H2 Zn finger 544..564 CDD:275368 11/19 (58%)
zf-H2C2_2 556..579 CDD:290200 10/19 (53%)
C2H2 Zn finger 572..592 CDD:275368 2/3 (67%)
zf-H2C2_2 584..607 CDD:290200
C2H2 Zn finger 600..620 CDD:275368
C2H2 Zn finger 628..648 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG26424
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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