DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dwg and LOC116411608

DIOPT Version :9

Sequence 1:	NP_477338.3	Gene:	dwg / 31265	FlyBaseID:	FBgn0000520	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	XP_031760062.1	Gene:	LOC116411608 / 116411608	-ID:	-	Length:	913	Species:	Xenopus tropicalis

Alignment Length:	463	Identity:	130/463 - (28%)
Similarity:	194/463 - (41%)	Gaps:	62/463 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 EEYVMIEMLNEEQENVANLDEELAEEDR-RIFAMTVDEEEEFLTEEVDQDDELSEEEHQLAQSGD 190
            :|.|..:.||..:.:...|.||.:.||. .|..:.:.|||.      |.|.:|:.||.......|
Frog    23 DELVSEDHLNPMERSAVLLSEEDSSEDEPEILKILIKEEEP------DSDYDLNPEESLEVPLAD 81

  Fly   191 QQEEHITMESVHEFQPAEVEYVTIKNEFETIVTEEDEFEVMNDSGAHDA-ILDC----QMIVIPA 250
            :..:...:.|..|....|......|:..::....||      .|.:.|| :..|    :...:..
Frog    82 EAGKIEPLLSTGECNTTESHRTRRKSRCDSRTRCED------SSASSDASVFTCCKCGKYFSLAR 140

  Fly   251 E-------------------GAIDEVIGE-ETLELEGDG--------------REEHLL------ 275
            |                   |....|..| |.:::...|              |..:||
Frog   141 ELAQHLHVCTGYSTESSRKAGVKPFVFTEYEKVQISPTGEKPFTCAECGKSFSRNSNLLAHRRLH 205

  Fly   276 ----PEAEDVCEDEDFLEESLDSAPPTAGEALPYVCTVCQKAFRQQCRLNQHMRSHVDEKQYECE 336
                |.|..||......:.:|.:.........|:.|..|:|:|.|:..|..|.:.|..||.:.|.
Frog   206 RGEKPFACKVCAKRFSQKNNLMAHERIHTGEKPFTCMECEKSFSQKSSLQAHKKIHTGEKPFVCT 270

  Fly   337 ECGKRLKHLRNYKEHMLTHTNVKPHQCSICGRFYRTTSSLAVHKRTHAEKKPYNCDQCGRGYAAF 401
            :|.||..|......||..||.:....||.||..:...|||..|::.||..||:.|.:||:.:...
Frog   271 DCLKRFSHKHQLVIHMSIHTGIAKFICSECGMSFSLKSSLQRHQKIHAGDKPFICTECGKRFCTK 335

  Fly   402 DHLRRHKLTHTGERPYACDLCDKAYYDSSSLRQHKISHTGKKAFTCEICGVGLSQKSGYKKHMMV 466
            ..|::|:.:||||:|:.|..|.|.:..:.:|..|:..|||.|.|:|..||...||||...:|..:
Frog   336 HELQKHQRSHTGEKPFVCKECGKCFATNRNLYVHQNVHTGAKPFSCPDCGKYFSQKSSLHRHQNI 400

  Fly   467 HSGVKAHKCDVCGHAFTFTSNLNAHVRLHSGEKPFKCEVCVKAFPTKKRLASHMRVHNKESPVTA 531
            |:|.|...|..||::|...|.|..|..:|:||||:.|..|.|:|..|..|..|.::|..|.|...
Frog   401 HTGAKPFTCTECGNSFALKSTLLRHQTIHTGEKPYSCTECGKSFSLKCTLRKHHKIHTGEKPFMC 465

  Fly   532 TVAVQSIN 539
            |...:..|
Frog   466 TECGKCFN 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dwg	NP_477338.3	zf-AD	14..91	CDD:214871
		COG5048	<297..451	CDD:227381	53/153 (35%)
		C2H2 Zn finger	307..327	CDD:275368	7/19 (37%)
		C2H2 Zn finger	335..355	CDD:275368	7/19 (37%)
		C2H2 Zn finger	363..383	CDD:275368	8/19 (42%)
		COG5048	<387..523	CDD:227381	52/135 (39%)
		C2H2 Zn finger	391..411	CDD:275368	5/19 (26%)
		zf-H2C2_2	403..426	CDD:290200	10/22 (45%)
		C2H2 Zn finger	419..439	CDD:275368	5/19 (26%)
		C2H2 Zn finger	447..467	CDD:275368	8/19 (42%)
		C2H2 Zn finger	475..495	CDD:275368	7/19 (37%)
		zf-H2C2_2	487..510	CDD:290200	10/22 (45%)
		C2H2 Zn finger	503..523	CDD:275368	7/19 (37%)
LOC116411608	XP_031760062.1	C2H2 Zn finger	129..177	CDD:275368	6/47 (13%)
		COG5048	175..541	CDD:227381	96/299 (32%)
		C2H2 Zn finger	185..205	CDD:275368	3/19 (16%)
		C2H2 Zn finger	213..233	CDD:275368	3/19 (16%)
		C2H2 Zn finger	241..261	CDD:275368	7/19 (37%)
		C2H2 Zn finger	269..289	CDD:275368	7/19 (37%)
		C2H2 Zn finger	297..317	CDD:275368	8/19 (42%)
		C2H2 Zn finger	325..345	CDD:275368	5/19 (26%)
		C2H2 Zn finger	353..373	CDD:275368	5/19 (26%)
		COG5048	377..812	CDD:227381	37/97 (38%)
		C2H2 Zn finger	381..401	CDD:275368	8/19 (42%)
		C2H2 Zn finger	409..429	CDD:275368	7/19 (37%)
		C2H2 Zn finger	437..457	CDD:275368	7/19 (37%)
		C2H2 Zn finger	465..485	CDD:275368	2/9 (22%)
		C2H2 Zn finger	493..513	CDD:275368
		C2H2 Zn finger	521..541	CDD:275368
		C2H2 Zn finger	571..591	CDD:275368
		C2H2 Zn finger	599..619	CDD:275368
		C2H2 Zn finger	627..647	CDD:275368
		C2H2 Zn finger	655..675	CDD:275368
		C2H2 Zn finger	683..703	CDD:275368
		C2H2 Zn finger	711..731	CDD:275368
		C2H2 Zn finger	739..759	CDD:275368
		C2H2 Zn finger	767..787	CDD:275368
		C2H2 Zn finger	795..815	CDD:275368
		C2H2 Zn finger	823..871	CDD:275368
		C2H2 Zn finger	824..843	CDD:275370
		C2H2 Zn finger	879..899	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910