DRSC/TRiP Functional Genomics Resources

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Protein Alignment dwg and Zfp988

DIOPT Version :9

Sequence 1:NP_477338.3 Gene:dwg / 31265 FlyBaseID:FBgn0000520 Length:592 Species:Drosophila melanogaster
Sequence 2:NP_001371161.1 Gene:Zfp988 / 115489950 MGIID:3651985 Length:633 Species:Mus musculus


Alignment Length:254 Identity:100/254 - (39%)
Similarity:135/254 - (53%) Gaps:30/254 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   304 PYVCTVCQKAFRQQCRLNQHMRSHVDEKQYECEECGK--------RLKHLR------NYK----- 349
            ||.|:.|.|.|.||..|:.|.|.|..||.|:|.||||        |: |.|      .||     
Mouse   323 PYKCSECDKCFTQQSCLSIHQRIHTGEKPYKCSECGKCFTEKSSLRI-HQRIHTGEKTYKCSECD 386

  Fly   350 ----------EHMLTHTNVKPHQCSICGRFYRTTSSLAVHKRTHAEKKPYNCDQCGRGYAAFDHL 404
                      .|...||..||::||.|.:.:...|:|.:|:|.|..:|||.|.:||:.:.....|
Mouse   387 KCFTRKFHLGIHQRIHTGEKPYKCSECDKCFTQQSNLTIHQRIHTGEKPYKCPECGKCFTEKSSL 451

  Fly   405 RRHKLTHTGERPYACDLCDKAYYDSSSLRQHKISHTGKKAFTCEICGVGLSQKSGYKKHMMVHSG 469
            |.|:..||||:||.|..|.|.:.:.||||.|:..|||:|.:.|..||...::||..:.|..:|:|
Mouse   452 RIHQRIHTGEKPYKCSECGKCFTEKSSLRIHQRIHTGEKPYKCNECGKCFTEKSSLRIHQRIHTG 516

  Fly   470 VKAHKCDVCGHAFTFTSNLNAHVRLHSGEKPFKCEVCVKAFPTKKRLASHMRVHNKESP 528
            .|.:||..||..||..|:|..|.|:|:||||:||..|.|.|..:..|:.|.|:|..|.|
Mouse   517 EKPYKCSECGKCFTVKSSLRIHQRIHTGEKPYKCSECDKCFTKQSNLSIHQRIHTGEKP 575

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dwgNP_477338.3 zf-AD 14..91 CDD:214871
COG5048 <297..451 CDD:227381 66/175 (38%)
C2H2 Zn finger 307..327 CDD:275368 9/19 (47%)
C2H2 Zn finger 335..355 CDD:275368 11/48 (23%)
C2H2 Zn finger 363..383 CDD:275368 7/19 (37%)
COG5048 <387..523 CDD:227381 59/135 (44%)
C2H2 Zn finger 391..411 CDD:275368 6/19 (32%)
zf-H2C2_2 403..426 CDD:290200 12/22 (55%)
C2H2 Zn finger 419..439 CDD:275368 8/19 (42%)
C2H2 Zn finger 447..467 CDD:275368 6/19 (32%)
C2H2 Zn finger 475..495 CDD:275368 9/19 (47%)
zf-H2C2_2 487..510 CDD:290200 12/22 (55%)
C2H2 Zn finger 503..523 CDD:275368 7/19 (37%)
Zfp988NP_001371161.1 KRAB 12..52 CDD:396083
C2H2 Zn finger 186..206 CDD:275368
C2H2 Zn finger 218..234 CDD:275368
COG5048 240..607 CDD:227381 100/254 (39%)
C2H2 Zn finger 242..262 CDD:275368
C2H2 Zn finger 270..290 CDD:275368
C2H2 Zn finger 298..318 CDD:275368
C2H2 Zn finger 326..346 CDD:275368 9/19 (47%)
C2H2 Zn finger 354..374 CDD:275368 8/20 (40%)
C2H2 Zn finger 382..402 CDD:275368 1/19 (5%)
C2H2 Zn finger 410..430 CDD:275368 7/19 (37%)
C2H2 Zn finger 438..458 CDD:275368 6/19 (32%)
C2H2 Zn finger 466..486 CDD:275368 8/19 (42%)
C2H2 Zn finger 494..514 CDD:275368 6/19 (32%)
C2H2 Zn finger 522..542 CDD:275368 9/19 (47%)
C2H2 Zn finger 550..570 CDD:275368 7/19 (37%)
C2H2 Zn finger 578..598 CDD:275368
C2H2 Zn finger 606..626 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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