DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dwg and LOC102547287

DIOPT Version :9

Sequence 1:	NP_477338.3	Gene:	dwg / 31265	FlyBaseID:	FBgn0000520	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	XP_006227880.2	Gene:	LOC102547287 / 102547287	RGDID:	7718701	Length:	549	Species:	Rattus norvegicus

Alignment Length:	352	Identity:	122/352 - (34%)
Similarity:	177/352 - (50%)	Gaps:	60/352 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   278 AEDVCEDED---------FLE--ESLDSA---------------PPT--------AGEALPYVCT 308
            ||::|:.|:         ||:  :.:.||               |.|        :||. ||.|.
  Rat   198 AENLCKCEECGKAFYLPSFLKQHQRIHSAENPYRCEECGKAFSYPSTLKQHQRIHSGEK-PYRCE 261

  Fly   309 VCQKAFRQQCRLNQHMRSHVDEKQYECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGRFYRTT 373
            .|.||||:....:||.|.|..||.|:||||||...:..|.|.|.:.|:.|||::|.:||..:||:
  Rat   262 ECGKAFRRSTYFHQHQRIHTGEKPYQCEECGKTFYYRSNLKGHQIIHSGVKPYKCDVCGSMFRTS 326

  Fly   374 SSLAVHKRTHAEKKPYNCDQCGRGYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLRQHKIS 438
            |.|:.|:|.|||.|.|:|::||:.::...:|.||||.|:.|:||.|:.|.|.:...|.|::|:..
  Rat   327 SDLSKHQRIHAEVKLYSCEECGKAFSTHSYLIRHKLGHSREKPYKCEECGKTFCYPSILKEHQRI 391

  Fly   439 HTGKKAFTCEICGVGLSQKSGYKKHMMVHSGVKAHKCDVCGHAFTFTSNLNAHVRLHSGEKPFKC 503
            |:|.|.:.|:|||.....:|...||..:|:.||.:.|:.||.||:..|.|..|...||||||:||
  Rat   392 HSGVKPYNCDICGSMFRTRSELSKHQRIHAEVKLYSCEECGKAFSTHSYLMRHRLGHSGEKPYKC 456

  Fly   504 EVCVKAFPTKKRLASHMRVHNKESPVTATVAVQSINPPSRQAGAEGATGGGA-------TGGSP- 560
            |.|.|::.....|..|.|:|: ::|....:           .|....|..|.       ||..|
  Rat   457 EECGKSYSYPSLLKEHQRIHS-QNPYKCDI-----------CGKVFCTRSGRSKHQRIHTGEKPY 509

  Fly   561 ----TGGGATGGSATNLH-ITEVHEQP 582
                .|.|.:..|...|| :....|:|
  Rat   510 KCEECGKGFSTHSYLTLHKLLHTEEKP 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dwg	NP_477338.3	zf-AD	14..91	CDD:214871
		COG5048	<297..451	CDD:227381	68/161 (42%)
		C2H2 Zn finger	307..327	CDD:275368	9/19 (47%)
		C2H2 Zn finger	335..355	CDD:275368	9/19 (47%)
		C2H2 Zn finger	363..383	CDD:275368	9/19 (47%)
		COG5048	<387..523	CDD:227381	55/135 (41%)
		C2H2 Zn finger	391..411	CDD:275368	8/19 (42%)
		zf-H2C2_2	403..426	CDD:290200	12/22 (55%)
		C2H2 Zn finger	419..439	CDD:275368	6/19 (32%)
		C2H2 Zn finger	447..467	CDD:275368	7/19 (37%)
		C2H2 Zn finger	475..495	CDD:275368	8/19 (42%)
		zf-H2C2_2	487..510	CDD:290200	13/22 (59%)
		C2H2 Zn finger	503..523	CDD:275368	7/19 (37%)
LOC102547287	XP_006227880.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910