DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dwg and LOC100537361

DIOPT Version :9

Sequence 1:	NP_477338.3	Gene:	dwg / 31265	FlyBaseID:	FBgn0000520	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	XP_003198540.5	Gene:	LOC100537361 / 100537361	-ID:	-	Length:	911	Species:	Danio rerio

Alignment Length:	239	Identity:	105/239 - (43%)
Similarity:	139/239 - (58%)	Gaps:	0/239 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   304 PYVCTVCQKAFRQQCRLNQHMRSHVDEKQYECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGR 368
            |..||:|.|:|||...|::|||:|..||.:.|.:|||......|:..||..||..||..|:.||:
Zfish   342 PITCTLCGKSFRQSSSLSKHMRTHTGEKPFTCTQCGKSFSQSSNFNLHMRIHTGEKPFTCTQCGK 406

  Fly   369 FYRTTSSLAVHKRTHAEKKPYNCDQCGRGYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLR 433
            .:|..|||..|.|||..:||:.|.|||:.:....||.:|...||||:|..|..|.|::..||||.
Zfish   407 SFRQASSLNKHMRTHTGEKPFTCTQCGKSFNRSSHLNQHIRIHTGEKPITCTQCGKSFRQSSSLY 471

  Fly   434 QHKISHTGKKAFTCEICGVGLSQKSGYKKHMMVHSGVKAHKCDVCGHAFTFTSNLNAHVRLHSGE 498
            :|...|||:|.|||..||...||.|.:..||.:|:|.|...|..||.:|..:|:|..|:|:|:||
Zfish   472 KHMRIHTGEKPFTCTQCGKSFSQSSNFNLHMRIHTGEKPITCTQCGKSFHQSSSLYKHMRIHTGE 536

  Fly   499 KPFKCEVCVKAFPTKKRLASHMRVHNKESPVTATVAVQSINPPS 542
            |||.|..|.|:|.....|..|||:|..|.|:|.|...:|....|
Zfish   537 KPFTCTQCGKSFRQASSLNKHMRIHTGEKPITCTQCGKSFRQSS 580

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dwg	NP_477338.3	zf-AD	14..91	CDD:214871
		COG5048	<297..451	CDD:227381	66/146 (45%)
		C2H2 Zn finger	307..327	CDD:275368	11/19 (58%)
		C2H2 Zn finger	335..355	CDD:275368	7/19 (37%)
		C2H2 Zn finger	363..383	CDD:275368	9/19 (47%)
		COG5048	<387..523	CDD:227381	61/135 (45%)
		C2H2 Zn finger	391..411	CDD:275368	7/19 (37%)
		zf-H2C2_2	403..426	CDD:290200	11/22 (50%)
		C2H2 Zn finger	419..439	CDD:275368	8/19 (42%)
		C2H2 Zn finger	447..467	CDD:275368	8/19 (42%)
		C2H2 Zn finger	475..495	CDD:275368	8/19 (42%)
		zf-H2C2_2	487..510	CDD:290200	12/22 (55%)
		C2H2 Zn finger	503..523	CDD:275368	8/19 (42%)
LOC100537361	XP_003198540.5	C2H2 Zn finger	37..53	CDD:275368
		C2H2 Zn finger	61..81	CDD:275368
		zf-H2C2_2	73..96	CDD:316026
		C2H2 Zn finger	89..109	CDD:275368
		C2H2 Zn finger	117..137	CDD:275368
		COG5048	141..557	CDD:227381	95/214 (44%)
		C2H2 Zn finger	145..165	CDD:275368
		C2H2 Zn finger	173..193	CDD:275368
		C2H2 Zn finger	205..225	CDD:275368
		C2H2 Zn finger	233..253	CDD:275368
		C2H2 Zn finger	261..281	CDD:275368
		C2H2 Zn finger	289..309	CDD:275368
		C2H2 Zn finger	317..337	CDD:275368
		C2H2 Zn finger	345..365	CDD:275368	11/19 (58%)
		C2H2 Zn finger	373..393	CDD:275368	7/19 (37%)
		C2H2 Zn finger	401..421	CDD:275368	9/19 (47%)
		COG5048	425..865	CDD:227381	68/156 (44%)
		C2H2 Zn finger	429..449	CDD:275368	7/19 (37%)
		C2H2 Zn finger	457..477	CDD:275368	8/19 (42%)
		C2H2 Zn finger	485..505	CDD:275368	8/19 (42%)
		C2H2 Zn finger	513..533	CDD:275368	8/19 (42%)
		C2H2 Zn finger	541..561	CDD:275368	8/19 (42%)
		C2H2 Zn finger	569..589	CDD:275368	3/12 (25%)
		C2H2 Zn finger	597..617	CDD:275368
		C2H2 Zn finger	625..645	CDD:275368
		C2H2 Zn finger	653..673	CDD:275368
		C2H2 Zn finger	681..701	CDD:275368
		C2H2 Zn finger	709..729	CDD:275368
		C2H2 Zn finger	737..757	CDD:275368
		C2H2 Zn finger	765..785	CDD:275368
		C2H2 Zn finger	793..813	CDD:275368
		C2H2 Zn finger	821..841	CDD:275368
		C2H2 Zn finger	849..869	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910