DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dwg and znf148

DIOPT Version :9

Sequence 1:	NP_477338.3	Gene:	dwg / 31265	FlyBaseID:	FBgn0000520	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	XP_031748753.1	Gene:	znf148 / 100487127	XenbaseID:	XB-GENE-996852	Length:	741	Species:	Xenopus tropicalis

Alignment Length:	187	Identity:	56/187 - (29%)
Similarity:	81/187 - (43%)	Gaps:	49/187 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   387 KPYNCDQCGRGYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLRQHKISHTGKKAFTCEICG 451
            |.:.|:.|...:....||:||...||||:|:.|..|:..:.....|::|:..|||:|.|.|:.||
Frog   123 KCHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCEMRFIQKYLLQRHEKIHTGEKPFHCDECG 187

  Fly   452 VGLSQKSGYKKHMMVHSGVKAHKCDVCGHAFTFTSNLNAHVRLHSGEKPFKCEVCVKAFPTKKRL 516
            :...|    |.||                        ..|.|.||||||::||.|::.|....|:
Frog   188 MRFIQ----KYHM------------------------ERHKRTHSGEKPYQCEYCLQYFSRTDRV 224

  Fly   517 ASHMRV--HNKESPVTATVAVQSINPPSRQAGAEGATGGG--ATGGSPTGGGATGGS 569
            ..|.|:  .|:|                |:.| :||..||  :..|.||.....||:
Frog   225 LKHKRMCHENRE----------------RKPG-KGAGKGGLLSPEGDPTLSPKDGGA 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dwg	NP_477338.3	zf-AD	14..91	CDD:214871
		COG5048	<297..451	CDD:227381	22/63 (35%)
		C2H2 Zn finger	307..327	CDD:275368
		C2H2 Zn finger	335..355	CDD:275368
		C2H2 Zn finger	363..383	CDD:275368
		COG5048	<387..523	CDD:227381	43/137 (31%)
		C2H2 Zn finger	391..411	CDD:275368	6/19 (32%)
		zf-H2C2_2	403..426	CDD:290200	11/22 (50%)
		C2H2 Zn finger	419..439	CDD:275368	4/19 (21%)
		C2H2 Zn finger	447..467	CDD:275368	7/19 (37%)
		C2H2 Zn finger	475..495	CDD:275368	2/19 (11%)
		zf-H2C2_2	487..510	CDD:290200	11/22 (50%)
		C2H2 Zn finger	503..523	CDD:275368	7/21 (33%)
znf148	XP_031748753.1	zf-C2H2	125..147	CDD:395048	6/21 (29%)
		C2H2 Zn finger	127..147	CDD:275368	6/19 (32%)
		zf-H2C2_2	139..164	CDD:404364	11/24 (46%)
		C2H2 Zn finger	155..175	CDD:275368	4/19 (21%)
		zf-H2C2_2	168..192	CDD:404364	10/23 (43%)
		C2H2 Zn finger	183..203	CDD:275368	9/47 (19%)
		zf-H2C2_2	195..220	CDD:404364	14/48 (29%)
		C2H2 Zn finger	211..229	CDD:275368	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910