DRSC/TRiP Functional Genomics Resources

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Protein Alignment dwg and zscan2

DIOPT Version :9

Sequence 1:NP_477338.3 Gene:dwg / 31265 FlyBaseID:FBgn0000520 Length:592 Species:Drosophila melanogaster
Sequence 2:XP_002943732.2 Gene:zscan2 / 100486661 XenbaseID:XB-GENE-6033591 Length:491 Species:Xenopus tropicalis


Alignment Length:340 Identity:110/340 - (32%)
Similarity:159/340 - (46%) Gaps:73/340 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   247 VIPAEGAIDEVIGEETLELEGDGREEHLLPEAEDVCEDEDFLEESLDSAPPTAGEALPYVCTVCQ 311
            ::|.|.|.:|.            .|:||...::.:|.:     .|..|...|:.:..|::||.|.
 Frog   141 IMPPESAANET------------SEQHLTAGSQTLCTN-----RSAKSQKKTSTKVKPFLCTTCG 188

  Fly   312 KAFRQQCRLNQHMRSHVDEKQYECEECGKRLKH----LRNYK----------------------- 349
            |.|.|:..|.||.|:|..|:.:.|.||||....    :|::|                       
 Frog   189 KRFSQKSLLIQHHRNHTGERPFPCIECGKSFTSCSLLIRHHKIHTGEKPFACSDCGKRFSESSQL 253

  Fly   350 -EHMLTHTNVKPHQCSICGRFYRTTSSLAVHKRTHAEKKPYNCDQCGRGYAAFDHLRRHKLTHTG 413
             .|..|||..:|:.|..||:.:..:|.|.:|:|||..::||:|..||:.::...||..||.||||
 Frog   254 VRHQRTHTGERPYTCIECGKSFSESSKLVIHQRTHTGERPYSCSDCGKSFSVRSHLITHKRTHTG 318

  Fly   414 ERPYACDLCDKAYYDSSSLRQHKISHTGKKAFTCEICGVGLSQKS-------------------- 458
            ||||.|:.|.|::.:||.|..|:..|||:|.:||..||...||:|                    
 Frog   319 ERPYTCNDCGKSFSESSKLVMHQRIHTGEKPYTCAACGKSFSQRSVLVTHQRIHTGEKPYTCPEC 383

  Fly   459 --------GYKKHMMVHSGVKAHKCDVCGHAFTFTSNLNAHVRLHSGEKPFKCEVCVKAFPTKKR 515
                    |..:|.:.||..|..:|.:||..|:..|:.|.|.|.|:||||:.|..|.|.|....:
 Frog   384 GKSFIDKVGCDRHRVTHSNEKPFQCLICGKNFSRNSDYNKHQRTHTGEKPYSCLECGKKFSWSYQ 448

  Fly   516 LASHMRVHNKESPVT 530
            |..|.|||..|.|.|
 Frog   449 LVRHQRVHTGEKPYT 463

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dwgNP_477338.3 zf-AD 14..91 CDD:214871
COG5048 <297..451 CDD:227381 65/181 (36%)
C2H2 Zn finger 307..327 CDD:275368 10/19 (53%)
C2H2 Zn finger 335..355 CDD:275368 8/47 (17%)
C2H2 Zn finger 363..383 CDD:275368 7/19 (37%)
COG5048 <387..523 CDD:227381 60/163 (37%)
C2H2 Zn finger 391..411 CDD:275368 7/19 (37%)
zf-H2C2_2 403..426 CDD:290200 15/22 (68%)
C2H2 Zn finger 419..439 CDD:275368 7/19 (37%)
C2H2 Zn finger 447..467 CDD:275368 8/47 (17%)
C2H2 Zn finger 475..495 CDD:275368 8/19 (42%)
zf-H2C2_2 487..510 CDD:290200 11/22 (50%)
C2H2 Zn finger 503..523 CDD:275368 7/19 (37%)
zscan2XP_002943732.2 COG5048 <68..314 CDD:227381 53/189 (28%)
C2H2 Zn finger 184..204 CDD:275368 10/19 (53%)
zf-H2C2_2 197..221 CDD:290200 11/23 (48%)
COG5048 208..>471 CDD:227381 86/256 (34%)
C2H2 Zn finger 212..232 CDD:275368 7/19 (37%)
zf-H2C2_2 225..248 CDD:290200 2/22 (9%)
C2H2 Zn finger 240..260 CDD:275368 1/19 (5%)
zf-H2C2_2 253..276 CDD:290200 8/22 (36%)
C2H2 Zn finger 268..288 CDD:275368 7/19 (37%)
zf-H2C2_2 281..304 CDD:290200 10/22 (45%)
C2H2 Zn finger 296..316 CDD:275368 7/19 (37%)
zf-H2C2_2 308..332 CDD:290200 15/23 (65%)
C2H2 Zn finger 324..344 CDD:275368 7/19 (37%)
zf-H2C2_2 337..361 CDD:290200 10/23 (43%)
C2H2 Zn finger 352..372 CDD:275368 6/19 (32%)
zf-H2C2_2 365..387 CDD:290200 0/21 (0%)
C2H2 Zn finger 380..400 CDD:275368 2/19 (11%)
zf-C2H2 406..428 CDD:278523 8/21 (38%)
C2H2 Zn finger 408..428 CDD:275368 8/19 (42%)
zf-H2C2_2 420..444 CDD:290200 11/23 (48%)
C2H2 Zn finger 436..456 CDD:275368 7/19 (37%)
zf-H2C2_2 449..471 CDD:290200 8/15 (53%)
C2H2 Zn finger 464..484 CDD:275368 110/340 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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