DRSC/TRiP Functional Genomics Resources

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Protein Alignment dwg and Zfp617

DIOPT Version :9

Sequence 1:NP_477338.3 Gene:dwg / 31265 FlyBaseID:FBgn0000520 Length:592 Species:Drosophila melanogaster
Sequence 2:XP_006253017.1 Gene:Zfp617 / 100361660 RGDID:2319713 Length:423 Species:Rattus norvegicus


Alignment Length:265 Identity:88/265 - (33%)
Similarity:133/265 - (50%) Gaps:30/265 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   291 SLDSAPPTAGEALPYVCTVCQKAFRQQCRLNQHMRSHVDEKQYECEECGKRLKHLRNYKEHMLTH 355
            ||.....|.....||.|..|:|||..:..:::||.:| :..:|:|..|.|...:....:||...|
  Rat   137 SLKKHKKTHSGEKPYKCKYCEKAFSYRYCVDRHMLTH-NTDRYKCRVCRKTFSNAIALREHKAIH 200

  Fly   356 TNVKPHQCSICGRFYRTTSSLAVHKRTHAEKKPYNCDQCGRGYAAFDHLRRHKLTHTGERPYACD 420
            :...| :|..|||.:.|:|||.:|||.|..:|.|.|..||:.:..:...:.||.|||||:||.|.
  Rat   201 SGEIP-ECKECGRMFWTSSSLDLHKRLHTTEKLYECKHCGKAFTGYCSFQLHKRTHTGEKPYECK 264

  Fly   421 LCDKAYYDSSSLRQHKISHTGKKAFTCEICGVGLSQKSGYKKHMMVHSGVKAHKCDVCGHAFTFT 485
            .|.|.:..||.::.||..|||:|.:.|..||...:.....::|:..|||...:||:|||.|:.:.
  Rat   265 QCGKTFRHSSHVQAHKRIHTGEKPYECMQCGKTFTSGHCARRHLGTHSGAWPYKCEVCGKAYPYV 329

  Fly   486 ----------------------------SNLNAHVRLHSGEKPFKCEVCVKAFPTKKRLASHMRV 522
                                        |:|..|...|:||||::|:.|.|||.....:.:|||.
  Rat   330 YSLRNHKKCHNEEKLYECKQCGKAFKCISSLRNHETTHTGEKPYECKECGKAFSCPSYIQNHMRT 394

  Fly   523 HNKES 527
            |.:::
  Rat   395 HKRQA 399

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dwgNP_477338.3 zf-AD 14..91 CDD:214871
COG5048 <297..451 CDD:227381 57/153 (37%)
C2H2 Zn finger 307..327 CDD:275368 7/19 (37%)
C2H2 Zn finger 335..355 CDD:275368 5/19 (26%)
C2H2 Zn finger 363..383 CDD:275368 11/19 (58%)
COG5048 <387..523 CDD:227381 54/163 (33%)
C2H2 Zn finger 391..411 CDD:275368 5/19 (26%)
zf-H2C2_2 403..426 CDD:290200 12/22 (55%)
C2H2 Zn finger 419..439 CDD:275368 7/19 (37%)
C2H2 Zn finger 447..467 CDD:275368 4/19 (21%)
C2H2 Zn finger 475..495 CDD:275368 8/47 (17%)
zf-H2C2_2 487..510 CDD:290200 10/22 (45%)
C2H2 Zn finger 503..523 CDD:275368 8/19 (42%)
Zfp617XP_006253017.1 KRAB 4..>44 CDD:214630
KRAB 4..43 CDD:279668
C2H2 Zn finger 125..145 CDD:275368 2/7 (29%)
zf-H2C2_2 137..162 CDD:290200 10/24 (42%)
COG5048 <149..307 CDD:227381 58/159 (36%)
C2H2 Zn finger 153..173 CDD:275368 7/19 (37%)
C2H2 Zn finger 180..200 CDD:275368 5/19 (26%)
C2H2 Zn finger 207..227 CDD:275368 11/19 (58%)
C2H2 Zn finger 235..255 CDD:275368 5/19 (26%)
zf-H2C2_2 247..272 CDD:290200 12/24 (50%)
COG5048 <259..418 CDD:227381 43/141 (30%)
C2H2 Zn finger 263..283 CDD:275368 7/19 (37%)
zf-H2C2_2 275..300 CDD:290200 9/24 (38%)
C2H2 Zn finger 291..311 CDD:275368 4/19 (21%)
C2H2 Zn finger 319..339 CDD:275368 5/19 (26%)
C2H2 Zn finger 347..367 CDD:275368 3/19 (16%)
zf-H2C2_2 359..384 CDD:290200 12/24 (50%)
C2H2 Zn finger 375..395 CDD:275368 8/19 (42%)
C2H2 Zn finger 402..422 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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