DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dwg and LOC100149352

DIOPT Version :9

Sequence 1:	NP_477338.3	Gene:	dwg / 31265	FlyBaseID:	FBgn0000520	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	XP_021330976.1	Gene:	LOC100149352 / 100149352	-ID:	-	Length:	238	Species:	Danio rerio

Alignment Length:	267	Identity:	71/267 - (26%)
Similarity:	114/267 - (42%)	Gaps:	51/267 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   277 EAEDV-------CEDEDFLEESLDSAPPTAGEALPYVCTVCQKAFRQQCRLNQHMRSHVDEKQYE 334
            |:||:       .:.|| :||.:|..|                       ||:.::.
Zfish    16 ESEDLRIAEVFSLKQED-IEEQIDLKP-----------------------LNEEIQE-------- 48

  Fly   335 CEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGRFYRTTSSLAVHKRTHAEKKPYNCDQCGRGYA 399
                ...:|..:|..|.......|:.:.||       .|......:.:......::|.:||:.:.
Zfish    49 ----PNEIKEEKNQLEEHHDFITVEQNSCS-------PTDERTTRETSQNTNSGFSCQRCGKSFV 102

  Fly   400 AFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLRQHKISHTGKKAFTCEICGVGLSQKSGYKKHM 464
            ...||:.|..|||||..:.|..|.|.:...::||.|...|..:.|..|:.||.....|..:::||
Zfish   103 KEGHLKNHSRTHTGESSFTCKQCGKGFTQKANLRNHTKLHAEESALFCQQCGKRFKLKKDFRRHM 167

  Fly   465 MVHSGVKAHKCDVCGHAFTFTSNLNAHVRLHSGEKPFKCEVCVKAFPTKKRLASHMRVHNKESPV 529
            ..|||.|.|||..||.:|...|:.|.|:.:|:||:.|.|..|.|:|.:...|.:|.::|.|.. |
Zfish   168 RGHSGEKPHKCLHCGKSFIDKSSANVHMSVHTGERSFVCAACGKSFASNANLINHRKIHLKRD-V 231

  Fly   530 TATVAVQ 536
            .:.|:|:
Zfish   232 LSAVSVE 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dwg	NP_477338.3	zf-AD	14..91	CDD:214871
		COG5048	<297..451	CDD:227381	29/153 (19%)
		C2H2 Zn finger	307..327	CDD:275368	2/19 (11%)
		C2H2 Zn finger	335..355	CDD:275368	3/19 (16%)
		C2H2 Zn finger	363..383	CDD:275368	3/19 (16%)
		COG5048	<387..523	CDD:227381	48/135 (36%)
		C2H2 Zn finger	391..411	CDD:275368	6/19 (32%)
		zf-H2C2_2	403..426	CDD:290200	11/22 (50%)
		C2H2 Zn finger	419..439	CDD:275368	6/19 (32%)
		C2H2 Zn finger	447..467	CDD:275368	6/19 (32%)
		C2H2 Zn finger	475..495	CDD:275368	7/19 (37%)
		zf-H2C2_2	487..510	CDD:290200	9/22 (41%)
		C2H2 Zn finger	503..523	CDD:275368	6/19 (32%)
LOC100149352	XP_021330976.1	C2H2 Zn finger	94..114	CDD:275368	6/19 (32%)
		zf-H2C2_2	106..131	CDD:316026	11/24 (46%)
		C2H2 Zn finger	122..142	CDD:275368	6/19 (32%)
		C2H2 Zn finger	150..170	CDD:275368	6/19 (32%)
		zf-H2C2_2	162..185	CDD:316026	11/22 (50%)
		C2H2 Zn finger	178..198	CDD:275368	7/19 (37%)
		C2H2 Zn finger	206..226	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910