DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dwg and zgc:173619

DIOPT Version :9

Sequence 1:	NP_477338.3	Gene:	dwg / 31265	FlyBaseID:	FBgn0000520	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_001103210.1	Gene:	zgc:173619 / 100006880	ZFINID:	ZDB-GENE-071004-58	Length:	217	Species:	Danio rerio

Alignment Length:	253	Identity:	81/253 - (32%)
Similarity:	120/253 - (47%)	Gaps:	38/253 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 FQPAEVEYVTIKNEFETIVTEEDEFEVMNDSGAHDAILDCQMIVIPAEGAIDEVIGEETLELEGD 268
            |...|.|.|.|:   ||...::::.:...|                   .|:|  .||:.|
Zfish     3 FIKEESEDVKIE---ETFTVKQEDLQEQTD-------------------LIEE--NEESKE---- 39

  Fly   269 GREEHLLPEAEDVCEDEDFLEESLDSAPPTAGEALPYVCTVCQKAFRQQCRLNQHMRSHVDEKQY 333
             .|.|:..|.::..:.:|.|:..         :...:.||.|.|:|.::..|..|||.|..||.:
Zfish    40 -EEHHVKIEEKNNLQTDDILKRR---------DKNHFTCTQCGKSFGRKTNLKIHMRIHTGEKPF 94

  Fly   334 ECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGRFYRTTSSLAVHKRTHAEKKPYNCDQCGRGY 398
            .|.:|||......|...||:.||..||.:|:.||:.:..:|.|..|.|.|..:||:.|.|||:.:
Zfish    95 TCNQCGKSFNQSSNLYTHMMIHTGEKPFKCTQCGKSFNRSSDLHQHMRIHTGEKPFTCTQCGKSF 159

  Fly   399 AAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLRQHKISHTGKKAFTCEICGVGLSQ 456
            ....||.:|...||||:|:.|..|.|::..||:.:||...|||:|.|||..||...||
Zfish   160 YCSSHLHQHMRIHTGEKPFTCSQCGKSFSQSSNFKQHMRIHTGEKPFTCTQCGKSFSQ 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dwg	NP_477338.3	zf-AD	14..91	CDD:214871
		COG5048	<297..451	CDD:227381	59/153 (39%)
		C2H2 Zn finger	307..327	CDD:275368	9/19 (47%)
		C2H2 Zn finger	335..355	CDD:275368	7/19 (37%)
		C2H2 Zn finger	363..383	CDD:275368	7/19 (37%)
		COG5048	<387..523	CDD:227381	32/70 (46%)
		C2H2 Zn finger	391..411	CDD:275368	7/19 (37%)
		zf-H2C2_2	403..426	CDD:290200	11/22 (50%)
		C2H2 Zn finger	419..439	CDD:275368	7/19 (37%)
		C2H2 Zn finger	447..467	CDD:275368	5/10 (50%)
		C2H2 Zn finger	475..495	CDD:275368
		zf-H2C2_2	487..510	CDD:290200
		C2H2 Zn finger	503..523	CDD:275368
zgc:173619	NP_001103210.1	COG5048	<64..217	CDD:227381	61/152 (40%)
		zf-C2H2	66..88	CDD:278523	9/21 (43%)
		C2H2 Zn finger	68..88	CDD:275368	9/19 (47%)
		zf-H2C2_2	80..105	CDD:290200	11/24 (46%)
		C2H2 Zn finger	96..116	CDD:275368	7/19 (37%)
		zf-H2C2_2	108..133	CDD:290200	10/24 (42%)
		C2H2 Zn finger	124..144	CDD:275368	7/19 (37%)
		zf-H2C2_2	139..159	CDD:290200	9/19 (47%)
		C2H2 Zn finger	152..172	CDD:275368	7/19 (37%)
		zf-H2C2_2	167..189	CDD:290200	9/21 (43%)
		C2H2 Zn finger	180..200	CDD:275368	7/19 (37%)
		zf-H2C2_2	192..217	CDD:290200	11/24 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910