DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vilya and Rnf212

DIOPT Version :9

Sequence 1:	NP_570026.1	Gene:	vilya / 31264	FlyBaseID:	FBgn0283545	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	XP_006535394.1	Gene:	Rnf212 / 671564	MGIID:	3645767	Length:	315	Species:	Mus musculus

Alignment Length:	167	Identity:	36/167 - (21%)
Similarity:	66/167 - (39%)	Gaps:	46/167 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 WIHCNSCCALFCD--KKHTFFLLACHHVFCERCVKVSAGRTPSDAPIFECSTCR---RSVRGRQL 77
            |:.||.|   |..  :|.:|.|.:|.||:|..|:......        ||..|:   ::|...:.
Mouse     4 WVFCNRC---FQSPHRKSSFSLTSCGHVYCHSCLLKGTKN--------ECVICQAPCQTVLLSKH 57

  Fly    78 TNSMPNHFKQLFHPEPFTIGND-----------FVETFQRGNHRHFDKYKERKELEMDKLFKDIE 131
            |||         :.:.|.:|.|           .:..||..:.|....:.:.|..::::     .
Mouse    58 TNS---------NIQTFFLGIDGLCKKYSQETSQISEFQEKHRRRLVAFYQEKISQLEE-----S 108

  Fly   132 VAKSVCQKRFLEAQMLRVERKKLMQRSRYIKAEVANR 168
            :.|||.|.:  :.|.:|..::....:   ||..|:.:
Mouse   109 LRKSVLQIK--QLQSMRSSQQPAFNK---IKNSVSTK 140

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vilya	NP_570026.1	zf-RING_5	20..70	CDD:291308	15/54 (28%)
vilya	NP_570026.1	Cut12	<112..170	CDD:288368	10/57 (18%)
Rnf212	XP_006535394.1	RING_Ubox	4..50	CDD:388418	16/56 (29%)
		comFA	6..>113	CDD:226583	27/131 (21%)
		RING-HC finger (C3HC4-type)	7..45	CDD:319361	14/48 (29%)
		PHA03247	<148..300	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22663
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100