DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vilya and ZCCHC14

DIOPT Version :9

Sequence 1:	NP_570026.1	Gene:	vilya / 31264	FlyBaseID:	FBgn0283545	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	NP_055959.2	Gene:	ZCCHC14 / 23174	HGNCID:	24134	Length:	1086	Species:	Homo sapiens

Alignment Length:	150	Identity:	31/150 - (20%)
Similarity:	60/150 - (40%)	Gaps:	40/150 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 HRHFDKYKERKELEMDKLF----KDIEVAKSVCQ--KRFLEAQMLRVERKKLMQR---------- 157
            |:::..:   |:|.|:|..    :|:...:|:..  |:.|:.| |.:|::|..:|
Human   448 HKYYPVF---KQLSMEKFLSLTEEDLNKFESLTMGAKKKLKTQ-LELEKEKSERRCLNPSAPPLV 508

  Fly   158 -----SRY--------IKAEVANRKAEMHRMAQAYRSRSLTSQSSSSAQRSARGRPRGRGTATQS 209
                 :|.        :::...:..||: |:........|..:.|||...|:...|.|      .
Human   509 TSSGVARVPPTSHVGPVQSGRGSHAAEL-RVEVEQPHHQLPREGSSSEYSSSSSSPMG------V 566

  Fly   210 SSRRRSTESAKRQQITSFIH 229
            .:|..|::||:.......||
Human   567 QAREESSDSAEENDRRVEIH 586

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vilya	NP_570026.1	zf-RING_5	20..70	CDD:291308
vilya	NP_570026.1	Cut12	<112..170	CDD:288368	14/86 (16%)
ZCCHC14	NP_055959.2	PX_domain	256..339	CDD:383026
		SAM_ZCCH14	431..495	CDD:188957	12/50 (24%)
		zf-CCHC	1045..1060	CDD:365871
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S11810
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950