Protein Alignment fs(1)Yb and Ddx46

DIOPT Version :9

• Sequence 1: NP_477494.2
• Gene: fs(1)Yb / 31262
• FlyBaseID: FBgn0000928
• Length: 1042
• Species: Drosophila melanogaster
• Sequence 2: NP_001268984.1
• Gene: Ddx46 / 212880
• MGIID: 1920895
• Length: 1032
• Species: Mus musculus
• Alignment Length: 948
• Identity: 170/948 - (17%)
• Similarity: 321/948 - (33%)
• Gaps: 312/948 - (32%)

  Fly    57 NFEAERLKFELAERDVNTILLPPHGAMVGQVLLLWSKGYINQALILCDGMLEHLGVVEANLVIHT 121
            ||:..:|:.|:.:|.              :.:..|.:....:|       :|::|.::
Mouse   150 NFDQNKLEEEMRKRK--------------ERVEKWREEQRKKA-------MENIGELK------- 186

  Fly   122 TLPELNKFEERLKWLSISARNAEMLVITPCDEENEKEGKGETEPEIVQQRMPLKVDALNSMQLY- 185
              .|:.:.::..|| |:.            |::::::...|.|.|..:    ::.:.|:.:..|
Mouse   187 --KEIEEMKQGKKW-SLE------------DDDDDEDDPAEAEKEGTE----MEDEELDPLDAYM 232

  Fly   186 -EIKENTPPTSSEDYKAEAD------------VLLSAATPATIPNDNKEQEINLSVEDATVKLLA 237
             |:||.....:....|..|.            |.:.....|.:..|.|:.|:..:.:||   :..
Mouse   233 EEVKEEVKKFNMRSVKGGAGNEKKSGPTVTKVVTVVTTKKAVVDADKKKGELMENDQDA---MEY 294

  Fly   238 SFELGSTD-SAAVDESSPAAAKFNAPV------YSPFVTENPTKSLDAEFQELVK-SFKVQNVFK 294
            |.|....| ..|:........|...||      |.||     .|:...|..||.| |.:..|||:
Mouse   295 SSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPF-----RKNFYVEVPELAKMSQEEVNVFR 354

  Fly   295 NMNLPPPPSVSIEEPVSSASASDYRHQIDTTSLDSIRTVKDSPASLAVVPFSAGGITYNNYG--- 356
                     :.:|                                         |||....|
Mouse   355 ---------LEME-----------------------------------------GITVKGKGCPK 369

  Fly   357 -VLGWSRHAVVPCYGLTEAPDISTIIRRAMQQMGVARSRARAVQRFAWPHVSLGKSVLVVGNLQI 420
             :..|     |.|       .||..|..::::.|.  .:...:|..|.|.:..|:.::.:.....
Mouse   370 PIKSW-----VQC-------GISMKILNSLKKHGY--EKPTPIQTQAIPAIMSGRDLIGIAKTGS 420

  Fly   421 GKTWSYLPTVCQRSHEDLQRRPDVGRGPTCIFVCPNQGQGKQI----ERWMSTL----LCLLGSA 477
            |||.::|..:.:  |...||..:.|.||..:.:.|.:....||    :::..||    :|:.|.
Mouse   421 GKTIAFLLPMFR--HIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGG- 482

  Fly   478 SGFEDVVTHWDKTQLVDIVRRLKKPVGILLTSVDLLLQLLNHNPVGSIFDAQAVKCIALDNLNDM 542
                        |.:.:.:..||:...|::.:...::.:|..|. |.:.:.:.|..:.||..:.|
Mouse   483 ------------TGISEQIAELKRGAEIIVCTPGRMIDMLAANS-GRVTNLRRVTYVVLDEADRM 534

  Fly   543 ---------VRVLPNDTMKLLQRLPEMFQLTQNKCQLLVSGRIWHTDLMVQHILPLMPDVLVLFD 598
                     :|::.|...   .|...||..|..:....::.||....:.||
Mouse   535 FDMGFEPQVMRIVDNVRP---DRQTVMFSATFPRAMEALARRILSKPIEVQ-------------- 582

  Fly   599 DALEASVYGG---VQLDVR---VVADEPEKIEHLKALIAERRNFANEPAVMVCSNSTEVL--LLR 655
                   .||   |..||.   :|.:|.:|...|..|:.   ::....:|::..:..|..  ||:
Mouse   583 -------VGGRSVVCSDVEQQVIVIEEEKKFLKLLELLG---HYQESGSVIIFVDKQEHADGLLK 637

  Fly   656 RSLQAIGVNAHICVSEACYSNVAEWLRQS-----PSGL--LLVTDDVVPR-LKCGKIPLLIHYSF 712
            ..::|    ::.|:|  .:..:.::.|.|     .:|.  |||...|..| |....:.|:::||.
Mouse   638 DLMRA----SYPCMS--LHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSC 696

  Fly   713 ASMWARFKNRF---------SLFYANLKSPTTRPVGQSVV------FAKPTDLENIWKLCDFYMK 762
            .:.:..:.:|.         ...|..:.....|..|..:.      .|.|.|||.:|.  ||  |
Mouse   697 PNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWS--DF--K 757

  Fly   763 HKLPRPGHLL---GILSQRRLEEQPTSRSLCHQMAAFGDCLRHKCMYRHVMWRDEVLPPDHYPKN 824
            .:....|.::   ...|.:..:...|.::|.::        |.|
Mouse   758 DQQKAEGKIIKKSSGFSGKGFKFDETEQALANE--------RKK--------------------- 793

  Fly   825 GLIRFLVLVCYSPAALAVRLSDQFPTAIRFLNFPMSDLGERVQRHYELEANRHMHPNPVPGEMAV 889
                      ...|||.::.||....|:        |:.|:::..:  .:.:.:.....||..:|
Mouse   794 ----------LQKAALGLQDSDDEDAAV--------DIDEQIESMF--NSKKRVKDMAAPGTSSV 838

  Fly   890 -VKNINRYERVHI-------------VSVESNVMVLVQ 913
             .......|::.|             :.:||.|.|:.|
Mouse   839 PAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQ 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fs(1)Yb	NP_477494.2	TUDOR	<859..948	CDD:278965	12/69 (17%)
Ddx46	NP_001268984.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..227		18/123 (15%)
		SrmB	344..826	CDD:223587	115/647 (18%)
		Q motif	372..400		7/41 (17%)
		DEADc	378..581	CDD:238167	44/223 (20%)
		DEAD box	529..532		1/2 (50%)
		Helicase_C	618..714	CDD:278689	20/101 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0334
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900