Protein Alignment CG2681 and Siah1b

DIOPT Version :10

• Sequence 1: NP_570022.2
• Gene: CG2681 / 31258
• FlyBaseID: FBgn0024997
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_033199.1
• Gene: Siah1b / 20438
• MGIID: 108063
• Length: 282
• Species: Mus musculus
• Alignment Length: 225
• Identity: 61/225 - (27%)
• Similarity: 94/225 - (41%)
• Gaps: 30/225 - (13%)

  Fly   180 SPATPSEEGP----PTVSARHYEGLIEELRCPGCAGAMKAPILLCKSGHSVCEQCTRILLMCPLC 240
            |...||:..|    .|.|......|.|   ||.|...:..|||.|:|||.||..|...|..||.|
Mouse    14 SKCPPSQRVPALTDTTASNNDLASLFE---CPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTC 75

  Fly   241 KEPFTNSRSLTVEALCAKAHFRCGHASGGCQVRMPVVLLPWHEQQCMYKPMKC-FMGRVWGDCRW 304
            :.|..:.|:|.:|.:.....|.|.:::.||::.:|......||:.|.::|..| ..|   ..|:|
Mouse    76 RGPLGSIRNLAMEKVANSVLFPCKYSASGCEITLPHTKKAEHEELCEFRPYSCPCPG---ASCKW 137

  Fly   305 QGREVQWKEHLEEQH--------DDRLFRSSSADL----EWNLGTRRKPLTGYYVFQAHDEMFNF 357
            ||.......||..||        :|.:|.::..:|    :|   ...:...|::.....::.
Mouse   138 QGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDW---VMMQSCFGFHFMLVLEKQ--- 196

  Fly   358 YEIHDRQRVLFTMTCTSNRRDSKYNFAYEV 387
             |.:|..:..|.:......|....||||.:
Mouse   197 -EKYDGHQQFFAIVQLIGTRKQAENFAYRL 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2681	NP_570022.2	RING_Ubox	206..250	CDD:473075	19/43 (44%)
		Sina	248..442	CDD:460824	35/153 (23%)
Siah1b	NP_033199.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		3/8 (38%)
		RING_Ubox	36..86	CDD:473075	21/52 (40%)
		Sina	82..278	CDD:460824	35/154 (23%)
		SBD. /evidence=ECO:0000250|UniProtKB:P61092	90..282		32/146 (22%)