Protein Alignment CG2681 and Siah1a

DIOPT Version :10

• Sequence 1: NP_570022.2
• Gene: CG2681 / 31258
• FlyBaseID: FBgn0024997
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: XP_006530847.3
• Gene: Siah1a / 20437
• MGIID: 108064
• Length: 355
• Species: Mus musculus
• Alignment Length: 231
• Identity: 65/231 - (28%)
• Similarity: 97/231 - (41%)
• Gaps: 32/231 - (13%)

  Fly   174 PSKPEKSPATPSEEGP----PTVSARHYEGLIEELRCPGCAGAMKAPILLCKSGHSVCEQCTRIL 234
            |:...|.|  ||:..|    .|.|......|.|   ||.|...:..|||.|:|||.||..|...|
Mouse    83 PTGTSKCP--PSQRVPALTGTTASNNDLASLFE---CPVCFDYVLPPILQCQSGHLVCSNCRPKL 142

  Fly   235 LMCPLCKEPFTNSRSLTVEALCAKAHFRCGHASGGCQVRMPVVLLPWHEQQCMYKPMKC-FMGRV 298
            ..||.|:.|..:.|:|.:|.:.....|.|.:||.||::.:|......||:.|.::|..| ..|
Mouse   143 TCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKAEHEELCEFRPYSCPCPG-- 205

  Fly   299 WGDCRWQGREVQWKEHLEEQH--------DDRLFRSSSADL----EWNLGTRRKPLTGYYVFQAH 351
             ..|:|||.......||..||        :|.:|.::..:|    :|   ...:...|::.....
Mouse   206 -ASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDW---VMMQSCFGFHFMLVL 266

  Fly   352 DEMFNFYEIHDRQRVLFTMTCTSNRRDSKYNFAYEV 387
            ::.    |.:|..:..|.:......|....||||.:
Mouse   267 EKQ----EKYDGHQQFFAIVQLIGTRKQAENFAYRL 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2681	NP_570022.2	RING_Ubox	206..250	CDD:473075	19/43 (44%)
		Sina	248..442	CDD:460824	37/153 (24%)
Siah1a	XP_006530847.3	RING_Ubox	109..159	CDD:473075	21/52 (40%)
		Sina	155..351	CDD:460824	37/154 (24%)