Protein Alignment CG2681 and siah-1

DIOPT Version :9

• Sequence 1: NP_570022.2
• Gene: CG2681 / 31258
• FlyBaseID: FBgn0024997
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_500409.1
• Gene: siah-1 / 177138
• WormBaseID: WBGene00021369
• Length: 419
• Species: Caenorhabditis elegans
• Alignment Length: 499
• Identity: 103/499 - (20%)
• Similarity: 174/499 - (34%)
• Gaps: 130/499 - (26%)

  Fly     7 GGKEEDLKILAQLKSIEQINEQRRIFLNSTINEEVPEATNGSTVREEDLEKNLKAIDEPQSTKMP 71
            ||..:|:        ||.:...:.||                   |||  .|..:...||:..:.
 Worm    10 GGDYQDV--------IESLRRTQLIF-------------------EED--DNNSSDSAPQANHLS 45

  Fly    72 PEEVAKKTPDEVPAQEQQKEPEKVEPAKPVPPNTLTLNVKYATLPSPNVVTLRSPLSPPPK---- 132
            ..:.:....:::........|       ||||.......:....|       |...|||..
 Worm    46 RHQTSNSLVEDMVNHSNGNPP-------PVPPGITQQQCQIGLTP-------RMSASPPSAVSTI 96

  Fly   133 --PPMLGRTRSTGPADGKGPASNGALSPDSSIIRQSFPEGVITPSKPEKS--PATPSEEGPPT-- 191
              ..:||:|.:...::..|                |.|....|.::..:|  |..|...|..|
 Worm    97 SGTAVLGKTMARVQSNPPG----------------SIPHNTTTTAQGIQSVAPHIPIGGGGATDD 145

  Fly   192 VSARHYEGLIEELRCPGCAGAMKAPILLCKSGHSVCEQCTRILLMCPLCKEPFTNSRSLTVEALC 256
            .||.    ::....||.|...|..|.:.|.|||.||..|...|..||.|:.|..:.|:|.:|.:.
 Worm   146 SSAE----ILSVFECPVCLEYMLPPYMQCSSGHLVCSNCRPKLQCCPTCRGPTPSVRNLGLEKIA 206

  Fly   257 AKAHFRCGHASGGCQVRMPVVLLPWHEQQCMYKPMKC-FMGRVWGDCRWQGREVQWKEHLEEQH- 319
            ....|.|..::.||.:.........||:.|.::|..| ..|   ..|:|||......|||::.|
 Worm   207 NTVRFPCKFSTSGCPLNFHHADKTEHEELCEFRPYCCPCPG---ASCKWQGGLSDVMEHLKKIHK 268

  Fly   320 -------DDRLFRSSSADL----EWNLGTRRKPLTGYYVFQAHDEMFNFYEIHDRQ--------- 364
                   :|.:|.::..:|    :|             |.......:||..:.::|
 Worm   269 SITTLQGEDIVFLATDINLPGAVDW-------------VMMQSCFDYNFMLVLEKQEKYDPAQPT 320

  Fly   365 RVLFTMTCTSNRRDSKYNFAYEVTVLLPDNEALSMTQKFPVHSEYDKDILMEGTCVSIPLTELNR 429
            ::.:.:......:....||.|.:        .||.::: .:..|.....:.||..|:|..::...
 Worm   321 QMFYAVVQLIGSKKEADNFVYRL--------ELSASRR-RMSWEATPRSIHEGVVVAIQQSDCLA 376

  Fly   430 F-------LDQDKVLHYRVSVLAVKSPRRAKPPRQNLPQPADLE 466
            |       ..::..|...|::..:.:|:|..|   |..:.:|||
 Worm   377 FDSNAAQLFAENGNLGINVTISRIDTPQRRHP---NELENSDLE 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2681	NP_570022.2	RING	206..244	CDD:238093	16/37 (43%)
		Sina	248..442	CDD:281181	41/222 (18%)
siah-1	NP_500409.1	RING	155..194	CDD:238093	16/38 (42%)
		Sina	197..396	CDD:281181	41/223 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3002
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1969
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45877
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.860