Protein Alignment CG2681 and Siah1

DIOPT Version :10

• Sequence 1: NP_570022.2
• Gene: CG2681 / 31258
• FlyBaseID: FBgn0024997
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_543181.2
• Gene: Siah1 / 140941
• RGDID: 620449
• Length: 282
• Species: Rattus norvegicus
• Alignment Length: 231
• Identity: 65/231 - (28%)
• Similarity: 97/231 - (41%)
• Gaps: 32/231 - (13%)

  Fly   174 PSKPEKSPATPSEEGP----PTVSARHYEGLIEELRCPGCAGAMKAPILLCKSGHSVCEQCTRIL 234
            |:...|.|  ||:..|    .|.|......|.|   ||.|...:..|||.|:|||.||..|...|
  Rat    10 PTGTSKCP--PSQRVPALTGTTASNNDLASLFE---CPVCFDYVLPPILQCQSGHLVCSNCRPKL 69

  Fly   235 LMCPLCKEPFTNSRSLTVEALCAKAHFRCGHASGGCQVRMPVVLLPWHEQQCMYKPMKC-FMGRV 298
            ..||.|:.|..:.|:|.:|.:.....|.|.:||.||::.:|......||:.|.::|..| ..|
  Rat    70 TCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKAEHEELCEFRPYSCPCPG-- 132

  Fly   299 WGDCRWQGREVQWKEHLEEQH--------DDRLFRSSSADL----EWNLGTRRKPLTGYYVFQAH 351
             ..|:|||.......||..||        :|.:|.::..:|    :|   ...:...|::.....
  Rat   133 -ASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDW---VMMQSCFGFHFMLVL 193

  Fly   352 DEMFNFYEIHDRQRVLFTMTCTSNRRDSKYNFAYEV 387
            ::.    |.:|..:..|.:......|....||||.:
  Rat   194 EKQ----EKYDGHQQFFAIVQLIGTRKQAENFAYRL 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2681	NP_570022.2	RING_Ubox	206..250	CDD:473075	19/43 (44%)
		Sina	248..442	CDD:460824	37/153 (24%)
Siah1	NP_543181.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		5/13 (38%)
		RING_Ubox	36..86	CDD:473075	21/52 (40%)
		Sina	82..278	CDD:460824	37/154 (24%)
		SBD. /evidence=ECO:0000250|UniProtKB:P61092	90..282		34/146 (23%)