Protein Alignment CG2680 and HDHD2

DIOPT Version :10

• Sequence 1: NP_570021.2
• Gene: CG2680 / 31257
• FlyBaseID: FBgn0024995
• Length: 305
• Species: Drosophila melanogaster
• Sequence 2: NP_115500.1
• Gene: HDHD2 / 84064
• HGNCID: 25364
• Length: 259
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 65/277 - (23%)
• Similarity: 106/277 - (38%)
• Gaps: 67/277 - (24%)

  Fly    25 VISDCDGVVWLLVGWIPNTGAAVNALKAAGKQIKFVSNNSFRSEEDYMEKFRHIGAKNVQEDDIV 89
            |:.|..|.:.:....:|....|:..|:.|...|:||:|.:..|::|.:|:.|.: ..::.||:|.
Human    10 VLVDLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLRKL-EFDISEDEIF 73

  Fly    90 HPVKTIVRYL---KKHKPGERVYSLMSLEANETLRKHNIEFESLQVKE-------------HLTA 138
            ..: |..|.|   |:.:|       |.|..:..|.    :|:.:|..:             |...
Human    74 TSL-TAARSLLERKQVRP-------MLLVDDRALP----DFKGIQTSDPNAVVMGLAPEHFHYQI 126

  Fly   139 ASLVDHLAIEKPVGAVLFDIHLDLSYVELAKAIRHLQENDDCQLIAGGSDVIMPLAENLNVAGFF 203
            .:....|.::   ||.|..||         || |:.:..|...|..|               .|.
Human   127 LNQAFRLLLD---GAPLIAIH---------KA-RYYKRKDGLALGPG---------------PFV 163

  Fly   204 DFLEHVKRYTQREATFLGKPSPILGEMFGEMFEIRDC--KRCIFIGDTLVQDVQFGKACGFQSLL 266
            ..||:.   |..:||.:|||..   ..|.|......|  :..:.|||....||...:..|...:|
Human   164 TALEYA---TDTKATVVGKPEK---TFFLEALRGTGCEPEEAVMIGDDCRDDVGGAQDVGMLGIL 222

  Fly   267 VLSG--CLTKEDMLNAP 281
            |.:|  ..:.|:.:|.|
Human   223 VKTGKYRASDEEKINPP 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2680	NP_570021.2	HAD_Pase_UmpH-like	24..295	CDD:319811	65/277 (23%)
HDHD2	NP_115500.1	HAD_PPase	8..255	CDD:319812	65/277 (23%)