DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2680 and Pdxp

DIOPT Version :9

Sequence 1:	NP_570021.2	Gene:	CG2680 / 31257	FlyBaseID:	FBgn0024995	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_001129291.1	Gene:	Pdxp / 727679	RGDID:	1586212	Length:	292	Species:	Rattus norvegicus

Alignment Length:	300	Identity:	90/300 - (30%)
Similarity:	133/300 - (44%)	Gaps:	51/300 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 VISDCDGVVWLLVGWIPNTGAAVNALKAAGKQIKFVSNNSFRSEEDYMEKFRHIGAKNVQEDDIV 89
            |:.|||||:|.....:|.....:..|..|||...||||||.|:..:...:|..:|...::.:::.
  Rat    22 VLFDCDGVLWNGERIVPGAPELLQRLAQAGKATLFVSNNSRRARPELALRFARLGFTGLRAEELF 86

  Fly    90 HPVKTIVRYLKKHKPGE-----RVYSLMSLEANETLRKHNIEFESLQVKEHLTAASLVDHLA--- 146
            .......|.|::..||.     .|:.|    ..|.||            ..|.||.|  .||
  Rat    87 SSAVCAARLLRQRLPGPPDAPGAVFVL----GGEGLR------------AELRAAGL--RLAGDP 133

  Fly   147 -IEKPVGAVL--FDIHLDLSYVELAKAIRHLQENDDCQLIAGGSDVIMPLAENLNVAGFFDFLEH 208
             .:..|.|||  :|.|  .|:.:|.:|..||:: .||.|:|...|...||.:.....|.......
  Rat   134 GDDPRVRAVLVGYDEH--FSFAKLTEACAHLRD-PDCLLVATDRDPWHPLTDGSRTPGTGSLAAA 195

  Fly   209 VKRYTQREATFLGKPSPILGEMFGEMFEIRDCKRCIFIGDTLVQDVQFGKACGFQSLLVLSGCLT 273
            |:..:.|:|..:|||||.:.:...|.|.: |..|.:.:||.|..|:.||..||..::|.|:|..:
  Rat   196 VETASGRQALVVGKPSPYMFQCITEDFSV-DPARMLMVGDRLETDILFGHRCGMTTVLTLTGVSS 259

  Fly   274 KEDMLNAPVEAQ-----------PDYYADSLADFTQLLEN 302
            .|       |||           |.||.:|:||..:.||:
  Rat   260 LE-------EAQAYLAAGQHDLVPHYYVESIADLMEGLED 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2680	NP_570021.2	HAD-SF-IIA	25..270	CDD:273637	77/255 (30%)
		Hydrolase_6	25..126	CDD:290083	30/105 (29%)
		Hydrolase_like	220..295	CDD:289983	28/85 (33%)
Pdxp	NP_001129291.1	PGP_euk	18..286	CDD:273635	87/292 (30%)
		Hydrolase_6	22..128	CDD:290083	34/123 (28%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:Q96GD0	58..60		1/1 (100%)
		Hydrolase_like	206..286	CDD:289983	29/87 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343742
Domainoid	1	1.000	60	1.000	Domainoid score	I10306
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D337140at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19288
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950