Protein Alignment CG2680 and Pdxp

DIOPT Version :9

• Sequence 1: NP_570021.2
• Gene: CG2680 / 31257
• FlyBaseID: FBgn0024995
• Length: 305
• Species: Drosophila melanogaster
• Sequence 2: NP_064667.2
• Gene: Pdxp / 57028
• MGIID: 1919282
• Length: 292
• Species: Mus musculus
• Alignment Length: 298
• Identity: 89/298 - (29%)
• Similarity: 129/298 - (43%)
• Gaps: 47/298 - (15%)

  Fly    25 VISDCDGVVWLLVGWIPNTGAAVNALKAAGKQIKFVSNNSFRSEEDYMEKFRHIGAKNVQEDDIV 89
            |:.|||||:|.....:|.....:..|..|||...||||||.|:..:...:|..:|...::.:.:.
Mouse    22 VLFDCDGVLWNGERIVPGAPELLQRLARAGKNTLFVSNNSRRARPELALRFARLGFAGLRAEQLF 86

  Fly    90 HPVKTIVRYLKKHKPGE-----RVYSLMSLEANETLRKHNIEFESLQVKEHLTAASLVDHLA--- 146
            .......|.|::...|.     .|:.|    ..|.||            ..|.||.|  .||
Mouse    87 SSALCAARLLRQRLSGPPDASGAVFVL----GGEGLR------------AELRAAGL--RLAGDP 133

  Fly   147 IEKP-VGAVLFDIHLDLSYVELAKAIRHLQENDDCQLIAGGSDVIMPLAENLNVAGFFDFLEHVK 210
            .|.| |.|||.......|:..|.:|..||:: .||.|:|...|...||::.....|.......|:
Mouse   134 GEDPRVRAVLVGYDEQFSFSRLTEACAHLRD-PDCLLVATDRDPWHPLSDGSRTPGTGSLAAAVE 197

  Fly   211 RYTQREATFLGKPSPILGEMFGEMFEIRDCKRCIFIGDTLVQDVQFGKACGFQSLLVLSGCLTKE 275
            ..:.|:|..:|||||.:.:...|.|.: |..|.:.:||.|..|:.||..||..::|.|:|..:.|
Mouse   198 TASGRQALVVGKPSPYMFQCITEDFSV-DPARTLMVGDRLETDILFGHRCGMTTVLTLTGVSSLE 261

  Fly   276 DMLNAPVEAQ-----------PDYYADSLADFTQLLEN 302
                   |||           |.||.:|:||..:.||:
Mouse   262 -------EAQAYLTAGQRDLVPHYYVESIADLMEGLED 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2680	NP_570021.2	HAD-SF-IIA	25..270	CDD:273637	76/253 (30%)
		Hydrolase_6	25..126	CDD:290083	29/105 (28%)
		Hydrolase_like	220..295	CDD:289983	28/85 (33%)
Pdxp	NP_064667.2	PGP_euk	18..286	CDD:273635	86/290 (30%)
		Hydrolase_6	22..128	CDD:290083	33/123 (27%)
		Substrate binding. /evidence=ECO:0000269|PubMed:24338687, ECO:0000269|PubMed:25783190, ECO:0007744|PDB:4BX2, ECO:0007744|PDB:5AES	58..60		1/1 (100%)
		Hydrolase_like	206..286	CDD:289983	29/87 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839900
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D982374at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19288
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950