Protein Alignment CG2680 and PDXP

DIOPT Version :9

• Sequence 1: NP_570021.2
• Gene: CG2680 / 31257
• FlyBaseID: FBgn0024995
• Length: 305
• Species: Drosophila melanogaster
• Sequence 2: NP_064711.1
• Gene: PDXP / 57026
• HGNCID: 30259
• Length: 296
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 92/304 - (30%)
• Similarity: 133/304 - (43%)
• Gaps: 55/304 - (18%)

  Fly    25 VISDCDGVVWLLVGWIPNTGAAVNALKAAGKQIKFVSNNSFRSEEDYMEKFRHIGAKNVQEDDIV 89
            |:.|||||:|.....:|.....:..|..|||...||||||.|:..:...:|..:|...::.:.:.
Human    22 VLFDCDGVLWNGERAVPGAPELLERLARAGKAALFVSNNSRRARPELALRFARLGFGGLRAEQLF 86

  Fly    90 HPVKTIVRYLKKHKPGE-----RVYSLMSLEANETLRKHNIEFESLQVKEHLTAASLVDHLAIEK 149
            .......|.|::..||.     .|:.|    ..|.||            ..|.||.|  .||.:.
Human    87 SSALCAARLLRQRLPGPPDAPGAVFVL----GGEGLR------------AELRAAGL--RLAGDP 133

  Fly   150 PVG--------AVL--FDIHLDLSYVELAKAIRHLQENDDCQLIAGGSDVIMPLAENLNVAGFFD 204
            ..|        |||  :|.|  .|:.:|.:|..||:: .:|.|:|...|...||::.....|...
Human   134 SAGDGAAPRVRAVLVGYDEH--FSFAKLREACAHLRD-PECLLVATDRDPWHPLSDGSRTPGTGS 195

  Fly   205 FLEHVKRYTQREATFLGKPSPILGEMFGEMFEIRDCKRCIFIGDTLVQDVQFGKACGFQSLLVLS 269
            ....|:..:.|:|..:|||||.:.|...|.|.| |..|.:.:||.|..|:.||..||..::|.|:
Human   196 LAAAVETASGRQALVVGKPSPYMFECITENFSI-DPARTLMVGDRLETDILFGHRCGMTTVLTLT 259

  Fly   270 GCLTKEDMLNAPVEAQ-----------PDYYADSLADFTQLLEN 302
            |....|       |||           |.||.:|:||.|:.||:
Human   260 GVSRLE-------EAQAYLAAGQHDLVPHYYVESIADLTEGLED 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2680	NP_570021.2	HAD-SF-IIA	25..270	CDD:273637	78/259 (30%)
		Hydrolase_6	25..126	CDD:290083	30/105 (29%)
		Hydrolase_like	220..295	CDD:289983	30/85 (35%)
PDXP	NP_064711.1	PGP_euk	18..290	CDD:273635	88/296 (30%)
		Substrate binding. /evidence=ECO:0000269|PubMed:18058037, ECO:0007744|PDB:2P27	58..60		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149855
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D337140at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19288
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850