DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2680 and Hdhd2

DIOPT Version :9

Sequence 1:	NP_570021.2	Gene:	CG2680 / 31257	FlyBaseID:	FBgn0024995	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_001014173.2	Gene:	Hdhd2 / 361351	RGDID:	1308579	Length:	384	Species:	Rattus norvegicus

Alignment Length:	271	Identity:	63/271 - (23%)
Similarity:	101/271 - (37%)	Gaps:	74/271 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 NTGAAVNA---------------LKAAGKQIKFVSNNSFRSEEDYMEKFRHIGAKNVQEDDIVHP 91
            |||..|..               |:||...::||:|.:..|:.|.:|:.|.:      |.||..
  Rat   137 NTGGRVTVPLLRSGVTLRSHLLLLRAASVMVRFVTNTTKESKRDLLERLRKL------EFDISE- 194

  Fly    92 VKTIVRYLKKHKPGERVYSLMSLEANETLRKHNIEFESLQVKEHLTAASLVDHLAIEKPVGAVLF 156
                          |.:::  ||.|...|      .|..||:..|    |||..|:....|....
  Rat   195 --------------EEIFT--SLTAARNL------IEQRQVRPML----LVDDRALPDFTGVQTH 233

  Fly   157 DIHLDLSYVELAKAIRHLQ-ENDDCQLIAGGSDVIMPLAENLNVAGFF-----------DFLEHV 209
            |.:..:  :.||....|.| .|:..:|:..|:.:|.     ::.|.::           .|:..:
  Rat   234 DPNAVV--IGLAPEHFHYQLLNEAFRLLLDGAPLIA-----IHKARYYKRKDGLALGPGPFVTAL 291

  Fly   210 KRYTQREATFLGKPSPILGEMFGEMFEIRDC--KRCIFIGDTLVQDVQFGKACGFQSLLVLSG-- 270
            :..|..:|..:|||..   ..|.|.....||  :..:.|||....||...:..|...:||.:|
  Rat   292 EYATDTKAVVVGKPEK---TFFLEALRDTDCAPEEAVMIGDDCRDDVDGAQNIGMLGILVKTGKY 353

  Fly   271 CLTKEDMLNAP 281
            ....|:.:|.|
  Rat   354 KAADEEKINPP 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2680	NP_570021.2	HAD-SF-IIA	25..270	CDD:273637	59/256 (23%)
		Hydrolase_6	25..126	CDD:290083	22/98 (22%)
		Hydrolase_like	220..295	CDD:289983	19/66 (29%)
Hdhd2	NP_001014173.2	Yos1	5..>64	CDD:285740
		HAD-SF-IIA-hyp3	122..382	CDD:162372	63/271 (23%)
		HAD_like	<159..>211	CDD:304363	19/80 (24%)
		Hydrolase_like	301..375	CDD:289983	19/67 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810