Protein Alignment CG2680 and PGP

DIOPT Version :9

• Sequence 1: NP_570021.2
• Gene: CG2680 / 31257
• FlyBaseID: FBgn0024995
• Length: 305
• Species: Drosophila melanogaster
• Sequence 2: NP_001035830.1
• Gene: PGP / 283871
• HGNCID: 8909
• Length: 321
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 95/327 - (29%)
• Similarity: 152/327 - (46%)
• Gaps: 53/327 - (16%)

  Fly     8 LKLSLEEQRQFIDSFDLVISDCDGVVWLLVGWIPNTGAAVNALKAAGKQIKFVSNNSFRSEEDYM 72
            ::||.|..:..:...|.::.|||||:|.....:|....|:.||:|.||::.|::|||.::...|.
Human    14 VRLSAERAQALLADVDTLLFDCDGVLWRGETAVPGAPEALRALRARGKRLGFITNNSSKTRAAYA 78

  Fly    73 EKFRHIG----AKNVQEDDIVHPVKTIVRYLKKH---KPGERVYSLMS--LEANETLRKHNIEFE 128
            ||.|.:|    |......::.........||::.   .|..:.|.|.|  |.|         |.|
Human    79 EKLRRLGFGGPAGPGASLEVFGTAYCTALYLRQRLAGAPAPKAYVLGSPALAA---------ELE 134

  Fly   129 SLQV------KEHLTAASLVD--HLAIEKPVGAVL--FDIHLDLSYVELAKAIRHLQENDDCQLI 183
            ::.|      .|.|......|  |..:|..|.||:  ||.|  .||::|.||:|:||: ..|.|:
Human   135 AVGVASVGVGPEPLQGEGPGDWLHAPLEPDVRAVVVGFDPH--FSYMKLTKALRYLQQ-PGCLLV 196

  Fly   184 AGGSDVIMPLAENLNVAGFFDFLEHVKRYTQREATFLGKPSPILGEMFGEMFEIRDCKRCIFIGD 248
            ....|..:||.....:||....:..|:...||:|..:||||..:.:...:.:.|.. :|.:.:||
Human   197 GTNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGINP-ERTVMVGD 260

  Fly   249 TLVQDVQFGKACGFQSLLVLSG--------------CLTKEDMLNAPVEAQPDYYADSLADFTQL 299
            .|..|:..|..||.:::|.|:|              |::|:.|:       ||:|.||:||....
Human   261 RLDTDILLGATCGLKTILTLTGVSTLGDVKNNQESDCVSKKKMV-------PDFYVDSIADLLPA 318

  Fly   300 LE 301
            |:
Human   319 LQ 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2680	NP_570021.2	HAD-SF-IIA	25..270	CDD:273637	79/263 (30%)
		Hydrolase_6	25..126	CDD:290083	31/109 (28%)
		Hydrolase_like	220..295	CDD:289983	24/88 (27%)
PGP	NP_001035830.1	PGP_euk	28..315	CDD:273635	90/306 (29%)
		Hydrolase_6	31..138	CDD:290083	33/115 (29%)
		Hydrolase_like	232..315	CDD:289983	25/90 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149844
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D337140at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19288
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850