Protein Alignment CG2680 and HDHD5

DIOPT Version :9

• Sequence 1: NP_570021.2
• Gene: CG2680 / 31257
• FlyBaseID: FBgn0024995
• Length: 305
• Species: Drosophila melanogaster
• Sequence 2: NP_149061.1
• Gene: HDHD5 / 27440
• HGNCID: 1843
• Length: 423
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 63/283 - (22%)
• Similarity: 105/283 - (37%)
• Gaps: 71/283 - (25%)

  Fly    28 DCDGVVWLLVGW--IPNTGAAVNALKAAGKQIK----FVSNNSFRSEEDYMEKFRHIGAKNVQED 86
            |.|||  |:.|.  ||....|...|..:..|::    ||:|.....:....::...:....|..|
Human    52 DIDGV--LVRGHRVIPAALKAFRRLVNSQGQLRVPVVFVTNAGNILQHSKAQELSALLGCEVDAD 114

  Fly    87 DIV---HPVKTIVRYLKKHKPGERVYSLMS-----LEANETLRKHNIEFESLQVKEHLTAASLVD 143
            .::   .|:|....|.:|.       .|:|     :|..:.|...|:    :.|.|...|..|:|
Human   115 QVILSHSPMKLFSEYHEKR-------MLVSGQGPVMENAQGLGFRNV----VTVDELRMAFPLLD 168

  Fly   144 HLAIEKPVGAVLFDIHLDLSYVE----LAKAIR---HLQENDDCQLIAG--GSDVIMP------- 192
            .:.:|:.:.......: |...:|    |.:.:|   .||...|..|..|  |:.:..|
Human   169 MVDLERRLKTTPLPRN-DFPRIEGVLLLGEPVRWETSLQLIMDVLLSNGSPGAGLATPPYPHLPV 232

  Fly   193 LAENLNV-------------AGFFDFLEHV-KRYTQREATF---LGKPSPILGEMFGEMFEIRDC 240
            ||.|:::             ..|...||.: ::.|.:|..:   :|||| ||...:.|....|..
Human   233 LASNMDLLWMAEAKMPRFGHGTFLLCLETIYQKVTGKELRYEGLMGKPS-ILTYQYAEDLIRRQA 296

  Fly   241 KR---------CIFIGDTLVQDV 254
            :|         ...:||..:.||
Human   297 ERRGWAAPIRKLYAVGDNPMSDV 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2680	NP_570021.2	HAD-SF-IIA	25..270	CDD:273637	63/283 (22%)
		Hydrolase_6	25..126	CDD:290083	25/111 (23%)
		Hydrolase_like	220..295	CDD:289983	13/44 (30%)
HDHD5	NP_149061.1	CECR5	47..360	CDD:200106	63/283 (22%)
		Hydrolase_6	49..152	CDD:290083	24/108 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900