DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG2680 and Hdhd5

DIOPT Version :9

Sequence 1:NP_570021.2 Gene:CG2680 / 31257 FlyBaseID:FBgn0024995 Length:305 Species:Drosophila melanogaster
Sequence 2:NP_659064.1 Gene:Hdhd5 / 214932 MGIID:2136976 Length:419 Species:Mus musculus


Alignment Length:387 Identity:73/387 - (18%)
Similarity:129/387 - (33%) Gaps:147/387 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 RHILKLSLE---------EQRQFI-------DSFDLVISDCDGVVWLLVGW--IPNTGAAVNALK 51
            ||:.||.:.         .:|.:|       .:|.|:. |.|||  |:.|.  ||....|.:.|.
Mouse    14 RHLWKLPVRLSAGLQGCGPRRGYIAGSAERSPTFGLLF-DIDGV--LVRGHRVIPAALEAFSKLV 75

  Fly    52 AAGKQIK----FVSNNSFRSEEDYMEKFRHIGAKNVQEDDIV---HPVKTIVRYLKKHKPGERVY 109
            .:..|::    ||:|.....:.:..::...:....|..|.::   .|:|..::|..|.       
Mouse    76 NSQGQLRVPVVFVTNAGNILQHNKAQELSDLLRCKVDPDQVILSHSPMKLFLQYHSKQ------- 133

  Fly   110 SLMSLEANETLRKHNIEFESLQVKEHLTAASLVDHLAIEKPVGAVLFDIHLDLSYVELAKAIRHL 174
            .|:|.:.........:.|:::..         :|.|.:..|          :|..|:|.:..:.:
Mouse   134 MLVSGQGPLVENARALGFQNVVT---------IDELRLAFP----------ELDMVDLQRRPKTM 179

  Fly   175 QENDDCQLIAG----GS------------DVIMP------------------LAENLNV------ 199
            :...|...|.|    |.            ||::.                  ||.|:::      
Mouse   180 RLRSDFPAIEGVLLLGEPVRWETNLQLIMDVLLSNGHPGTGLATAPYPHLPVLASNMDLLWMAEA 244

  Fly   200 -------AGFFDFLEHV-KRYTQREATF---LGKPSPILGEMFGE-----MFEIR----DCKRCI 244
                   ..|...||.: ::.|..|..:   :|||| ||...:.|     ..|.|    ..::..
Mouse   245 KMPRFGHGTFLLCLETIYRKITGNELKYEGLMGKPS-ILTYQYAEDVIRQQAERRGWAAPIRKLY 308

  Fly   245 FIGDTLVQDV--------------------QFG----------KACGFQSLLVLSGCLTKED 276
            .|||..:.||                    |.|          ::|.  |:||.:|..:.:|
Mouse   309 AIGDNPMSDVYGANLFHQYLQMANRGEEEQQTGGQQKQRPSATQSCA--SILVCTGIYSSQD 368

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2680NP_570021.2 HAD-SF-IIA 25..270 CDD:273637 63/343 (18%)
Hydrolase_6 25..126 CDD:290083 22/109 (20%)
Hydrolase_like 220..295 CDD:289983 22/96 (23%)
Hdhd5NP_659064.1 CECR5 47..358 CDD:200106 63/342 (18%)
Hydrolase_6 49..152 CDD:290083 23/112 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0647
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.