Protein Alignment eIF2Bbeta and GCD2

DIOPT Version :9

• Sequence 1: NP_570020.1
• Gene: eIF2Bbeta / 31256
• FlyBaseID: FBgn0024996
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_011597.1
• Gene: GCD2 / 852974
• SGDID: S000003315
• Length: 651
• Species: Saccharomyces cerevisiae
• Alignment Length: 389
• Identity: 82/389 - (21%)
• Similarity: 138/389 - (35%)
• Gaps: 116/389 - (29%)

  Fly    32 LDIFKYIIMSKSWQNADA------LMQIVRDQCKILQAALPQETVTSNIARRILKLTREEFDLLH 90
            |::|:.:|  |.:|....      |...:..|..:|:.|.|......|..|.:    ::|..|
Yeast   297 LEVFQIVI--KDYQTPKGTTLSRNLTSYLSHQIDLLKKARPLSVTMGNAIRWL----KQEISL-- 353

  Fly    91 AKVQHFADDSQASLSLHKLVTQTSESNVSVDYSVPQHGLREALLDHL-QEVETELETSSENICVQ 154
                                         :|.|.|....::.|.:.: |..:.::|.:.:.|...
Yeast   354 -----------------------------IDPSTPDKAAKKDLCEKIGQFAKEKIELADQLIIDN 389

  Fly   155 AEEHIHSSEIILTLGHSRSV-ENFLKRAIKKRQFLTIIVAECAPACRGHNLAASLANE-KNVEIV 217
            |...|..|..|:|.|.|:.: |..|..||..::.:.:||.:..|...|..:|.:|.|. .||...
Yeast   390 ASTQIEESTTIVTYGSSKVLTELLLHNAISLKKNIKVIVVDSRPLFEGRKMAETLRNAGVNVMYA 454

  Fly   218 VIPDA-AIFAMMSRVNKVIIGTHSVLANGGLRAACGAYTVALAAKHYSVPVIVLAPMYKLSPLHL 281
            :|... .||.|  .|:.|.:|.||:|:||.|.:..|...:|::||..::||:|.....|.|....
Yeast   455 LITSLDTIFNM--DVDYVFLGAHSILSNGFLYSRAGTAMLAMSAKRRNIPVLVCCESLKFSQRVQ 517

  Fly   282 CEQDAFNMVGCAEDV--IPYDSIPAR--------------------------------------- 305
            .:...||.:....|:  |.|::...|
Yeast   518 LDSVTFNELADPNDLVNIDYENPVERRGNKGALLNQFIKERKFEKKKLAMENKPKGNKIGGKKGS 582

  Fly   306 --EAK------------------------VYSPMFDYVPPELVTLFISNTGGHAPSYVYRLLTE 343
              |:|                        :.:.::|..|||.:...|:..|...||.|..:|.|
Yeast   583 EGESKDASNEEDSNSKNILDGWQELPSLNIVNILYDLTPPEYIKKVITEFGALPPSSVPVILRE 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bbeta	NP_570020.1	GCD2	8..345	CDD:275543	82/389 (21%)
		IF-2B	21..334	CDD:279362	77/378 (20%)
GCD2	NP_011597.1	PHA03255	120..>232	CDD:165513
		IF-2B	285..637	CDD:395798	77/378 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810