Protein Alignment eIF2Bbeta and GCD7

DIOPT Version :9

• Sequence 1: NP_570020.1
• Gene: eIF2Bbeta / 31256
• FlyBaseID: FBgn0024996
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_013394.1
• Gene: GCD7 / 850998
• SGDID: S000004282
• Length: 381
• Species: Saccharomyces cerevisiae
• Alignment Length: 373
• Identity: 113/373 - (30%)
• Similarity: 180/373 - (48%)
• Gaps: 47/373 - (12%)

  Fly     9 ITQLIHAIKVGLVEGSYNITNKTLDIFKYIIMSKSWQNADALMQIVRDQCKILQAALPQETVTSN 73
            |...:..:|...|:|||.|..:||.:....|.:..|.:.:.|::.:||....|:.|.|......|
Yeast    22 IDTFVAKLKRRQVQGSYAIALETLQLLMRFISAARWNHVNDLIEQIRDLGNSLEKAHPTAFSCGN 86

  Fly    74 IARRILKLTREE-----------------------FDLLHAKVQHFADDSQASLSLHKLVTQTSE 115
            :.||||.:.|:|                       |:||....|...:...:|.|        |.
Yeast    87 VIRRILAVLRDEVEEDTMSTTVTSTSVAEPLISSMFNLLQKPEQPHQNRKNSSGS--------SS 143

  Fly   116 SNVSVDYSVPQHGLREALLDHLQEVETELETSSENICVQAEEHIHSSEIILT-LGHSRSVENFL- 178
            .....||       |:..:..::::..|::...|.|...|.:.||..||:|| ...|::|..||
Yeast   144 MKTKTDY-------RQVAIQGIKDLIDEIKNIDEGIQQIAIDLIHDHEILLTPTPDSKTVLKFLI 201

  Fly   179 -KRAIKKRQFLTIIVAECAP--ACRGHNLAASLANEKNVEIVVIPDAAIFAMMSRVNKVIIGTHS 240
             .|....|.| |::|.|..|  ....|..|..|| :.|:|.:|:||:|:||:||||.||||||.:
Yeast   202 TARERSNRTF-TVLVTEGFPNNTKNAHEFAKKLA-QHNIETLVVPDSAVFALMSRVGKVIIGTKA 264

  Fly   241 VLANGG-LRAACGAYTVALAAKHYSVPVIVLAPMYKLSPLHLCEQDAFNMVGCAEDVIPYDSIPA 304
            |..||| :.:..|..:|...|:.:..||..:|.:||||||:..:.:.|...|.::.::|... |.
Yeast   265 VFVNGGTISSNSGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKFVEFGGSQRILPRMD-PR 328

  Fly   305 REAKVYSPMFDYVPPELVTLFISNTGGHAPSYVYRLLTELYHPEDLEI 352
            :.....:.:.||||||.:.::|:|.||..||::||:..:.|...|:.:
Yeast   329 KRLDTVNQITDYVPPENIDIYITNVGGFNPSFIYRIAWDNYKQIDVHL 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bbeta	NP_570020.1	GCD2	8..345	CDD:275543	111/364 (30%)
		IF-2B	21..334	CDD:279362	105/341 (31%)
GCD7	NP_013394.1	GCD2	17..370	CDD:224105	111/365 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344035
Domainoid	1	1.000	141	1.000	Domainoid score	I1015
eggNOG	1	0.900	-	-		E1_COG1184
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6507
Inparanoid	1	1.050	153	1.000	Inparanoid score	I1103
Isobase	1	0.950	-	0	Normalized mean entropy	S1701
OMA	1	1.010	-	-		QHG54382
OrthoFinder	1	1.000	-	-		FOG0005038
OrthoInspector	1	1.000	-	-		oto99049
orthoMCL	1	0.900	-	-		OOG6_102470
Panther	1	1.100	-	-	LDO	PTHR45859
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R372
SonicParanoid	1	1.000	-	-		X4090
TreeFam	1	0.960	-	-
	16	15.740