Protein Alignment eIF2Bbeta and Eif2b2

DIOPT Version :9

• Sequence 1: NP_570020.1
• Gene: eIF2Bbeta / 31256
• FlyBaseID: FBgn0024996
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_114447.2
• Gene: Eif2b2 / 84005
• RGDID: 620820
• Length: 351
• Species: Rattus norvegicus
• Alignment Length: 348
• Identity: 163/348 - (46%)
• Similarity: 235/348 - (67%)
• Gaps: 15/348 - (4%)

  Fly     8 EITQLIHAIKVGLVEG-----SYNITNKTLDIFKYIIMSKSWQNADALMQIVRDQCKILQAALPQ 67
            |:::.|.:....|..|     |.::..:||.:.:.:|....|.||..||.::|.:.:.:.||.|.
  Rat    10 ELSERIESFVETLKRGGGRRSSEDMARETLGLLRRLITDHHWNNAGDLMDLIRREGRRMTAAQPS 74

  Fly    68 ETVTSNIARRILKLTREEFDLLHAKVQHFADDSQASLSLHKLVTQTSESNVSVDYSVPQHGLREA 132
            ||...|:.||:||:.|||:..||.:    :|:|....|||||:|   ...:|.|:|.....|:..
  Rat    75 ETTVGNMVRRVLKIIREEYGRLHGR----SDESDQQESLHKLLT---SGGLSEDFSFHYAPLKSN 132

  Fly   133 LLDHLQEVETELETSSENICVQAEEHIHSSEIILTLGHSRSVENFLKRAIKKRQFLTIIVAECAP 197
            :::.:.|:..|||.::|||..||.|||||:|:|:|:|.||:||.||:.|.:||:| .:|.|||||
  Rat   133 IIEAINELLVELEGTTENIAAQALEHIHSNEVIMTIGFSRTVEAFLREAAQKRKF-HVIAAECAP 196

  Fly   198 ACRGHNLAASLANEKNVEIVVIPDAAIFAMMSRVNKVIIGTHSVLANGGLRAACGAYTVALAAKH 262
            .|:||.:|.:| :|..:|..|:.||||||:|||||||||||.::||||.|||..|.:|:||||||
  Rat   197 FCQGHEMAVNL-SEAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGSLRAVAGTHTLALAAKH 260

  Fly   263 YSVPVIVLAPMYKLSPLHLCEQDAFNMVGCAEDVIPY-DSIPAREAKVYSPMFDYVPPELVTLFI 326
            :|.|:||.|||:||||....|:|:|:.....|:|:|: :.....:..|:.|:||||||:|:||||
  Rat   261 HSTPLIVCAPMFKLSPQFPSEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPDLITLFI 325

  Fly   327 SNTGGHAPSYVYRLLTELYHPED 349
            ||.||:||||||||::|||||:|
  Rat   326 SNIGGNAPSYVYRLMSELYHPDD 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bbeta	NP_570020.1	GCD2	8..345	CDD:275543	158/342 (46%)
		IF-2B	21..334	CDD:279362	146/318 (46%)
Eif2b2	NP_114447.2	GCD2	13..344	CDD:224105	157/339 (46%)
		IF-2B	29..333	CDD:279362	145/312 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341720
Domainoid	1	1.000	278	1.000	Domainoid score	I1645
eggNOG	1	0.900	-	-		E1_COG1184
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6507
Inparanoid	1	1.050	306	1.000	Inparanoid score	I2555
OMA	1	1.010	-	-		QHG54382
OrthoDB	1	1.010	-	-		D396237at33208
OrthoFinder	1	1.000	-	-		FOG0005038
OrthoInspector	1	1.000	-	-		oto95709
orthoMCL	1	0.900	-	-		OOG6_102470
Panther	1	1.100	-	-	LDO	PTHR45859
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4090
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770