Protein Alignment eIF2Bbeta and eif2b1

DIOPT Version :10

• Sequence 1: NP_570020.1
• Gene: eIF2Bbeta / 31256
• FlyBaseID: FBgn0024996
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: XP_012818935.2
• Gene: eif2b1 / 550040
• XenbaseID: XB-GENE-972471
• Length: 356
• Species: Xenopus tropicalis
• Alignment Length: 309
• Identity: 81/309 - (26%)
• Similarity: 135/309 - (43%)
• Gaps: 49/309 - (15%)

  Fly    65 LPQET-VTSNIA--RRILK-LTREEFDLLHAKVQHFAD--------DSQASLS-----LHKLVTQ 112
            |.::| |.:.:|  |.:|: |.|:..:.:...:....|        ||..|:|     ..:.:|.
 Frog    68 LQEDTDVATAVAAIRTLLEFLKRDTGETIQGLIGSLKDATGTLSKVDSSVSVSSGGELFLRFITL 132

  Fly   113 TSESNVSVDYS-----VPQHGLREALLDHLQEVETELETSSENICVQAEEHIHSSEIILTLGHSR 172
            ||....| ||.     :.:.|  |..|..:.....::.|    :|.   ..|.....|||..:|:
 Frog   133 TSNLEHS-DYDKCKKMMSERG--ELFLKRISMSRNKITT----LCC---PFIKDGAKILTHAYSK 187

  Fly   173 SVENFLKRAIKKRQFLTIIVAECAPACRGHNLAASLANEKNVEIVVIPDAAIFAMMSRVNKVIIG 237
            .|...|:.|...:.| ::.|.|..|...|..:..:|.| :||.:.:|.|||:..:|.:|:.||:|
 Frog   188 VVLKVLEEAAANKNF-SVYVTESQPDLSGKIMVEALRN-RNVPVTLILDAAVGYIMEKVDLVIVG 250

  Fly   238 THSVLANGGLRAACGAYTVALAAKHYSVPVIVLAPMYK---LSPLHLCEQDAFNMVGCAEDVIPY 299
            ...|:.:||:....|...:|:.||..:.|..|:|..:|   |.||:  ::|       ..|...|
 Frog   251 AEGVVESGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLN--QRD-------VPDKFKY 306

  Fly   300 DSIPAREAK---VYSPMFDYVPPELVTLFISNTGGHAPSYVYRLLTELY 345
            .:...::.|   ...|..||..|.|:||..::.|...||.:...|.:||
 Frog   307 KADTQQQNKDLLEEHPWIDYTSPSLITLLFTDLGVLTPSAISDELIKLY 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bbeta	NP_570020.1	IF-2B	21..334	CDD:395798	76/296 (26%)
eif2b1	XP_012818935.2	IF-2B	69..344	CDD:395798	75/295 (25%)